Category Archives: Data Mining
How agile methodologies can boost the digital transformation of the mining industry – BNamericas English
As digital transformation gains ground in the mining industry, new ways of working are being developed to quickly create and implement successful solutions.
BNamericas interviewed Matas Corrales, CEO of Kolossus, a Chilean company that develops solutions to improve production processes using agile methodologies and collaborative work, to learn how this is applied and how it benefits the industry.
BNamericas: Is it possible to achieve greater effectiveness in project execution within the mining industry by going beyond digital transformation?
Corrales:Yes, through agile methodologies such as Scrum, 100% project effectiveness can be achieved.
The mining industry and its suppliers are used to developing long-term projects delivering a solution after 12 months of work, but with agile methodologies we build the solution jointly with the client and results are delivered every month.
BNamericas:Do you think that the Chilean mining industry 4.0 roadmap has helped clients trust in agile methodologies?
Corrales: Yes, although this is just starting, the 4.0 roadmap gave it a boost.
The industry currently generates a lot of data, but sometimes they dont know what to do with it. Its necessary to generate more data management, do data mining as well as develop strategies to access the data efficiently and instantly.
BNamericas:But large-scale mining is already working on that ...
Corrales:Yes, but not medium-sized mining. There they continue to make decisions 30 days apart. They dont get instant information like large companies do.
BNamericas: How do you guarantee data security?
Corrales:A year ago cybersecurity became more important. We dont believe in datacenters, because having a rack full of processing equipment is very expensive and doesnt have the same processing capacity as a global datacenter such as Amazon, Huawei, Google or Microsoft, for example.
Back then we used to build that security, we built telecommunications equipment, we had firewalls, virtual private networks and we believed it was secure. Now we work with a virtual security that has several layers before reaching your data.
Now were talking about how you treat that data securely.
BNamericas: Within the mining process, where can agile methodologies be applied?
Corrales: The first thing is to collect the data and then manage it efficiently to reduce costs, prioritize workers safety as well as improve training through e-learning, for example, which also helps to deconcentrate and fast-track the delivery of certifications.
BNamericas:Within the mining industry, are digital transformation projects driven solely by the productive areas?
Corrales:I would say that the human resources areas are the ones promoting more projects in order to facilitate controls and compliance with regulations.
The production and maintenance areas are super important, but its very difficult to convince managers to implement changes because they already have their processes structured.
BNamericas:Are there any obstacles for the development of these methodologies within the industry?
Corrales:In Chile, its difficult to convince companies to switch to virtual infrastructures.
In mining it happens that clients ask to see a Gantt chart with dates for each execution, but in agile methodologies theres no Gantt chart, we work with user logs, its a continuous process and with deliverables.
Its difficult to convince them that datacenters are not as effective as the cloud.
BNamericas: Is migrating to agile methodologies cheaper?
Corrales:Its cheaper, but you must break paradigms. Ill give you an example. You invested millions of dollars in a datacenter, and although the monthly maintenance cost isnt high, as technology advances you have to renew some equipment.
By migrating to agile methodologies, I do a monthly investment in having the cloud available to handle large amounts of data.
Back then, I used to spend a lot of money in the long term and only 30% of projects involving new technologies worked. Now the expense is monthly, but in the long term its less [expensive] and more successful than traditional processes.
BNamericas:Are you currently developing any solution for large or medium-scale mining companies in Chile?
Corrales:I cant mention companies or processes, but were developing some focused on the control of human capital. Not only the training of human capital, but how they enter, move within and leave the mine.
Photo credit: Kolossus
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If youre a little vague about big data and what it means, this package will clear it all – Illinoisnewstoday.com
Netflix big data NS Save, manage and optimize terabytes of viewer data every day. AccuWeather uses it Create AI-powered forecasts..And Etsy takes advantage of big data Take advantage of machine learning In the balance between commerce and community building. Large companies are already leveraging the benefits of data collection and analytics to drive their businesses, but small businesses are also increasingly taking advantage of these features.
In training at 2021 Big Data Certified Super Training BundleLearners can delve into data analysis phenomena themselves and become a source of real-world understanding of this groundbreaking new realm.
Data science is the future and filled with over 113 hours of training, this 15-course package uses powerful new tools to organize and interpret your data and see what those numbers really mean. Guide all students through the process of knowing how to know.
Since the Python programming language is the foundation of todays data science, this bundle begins with a few courses to help users become accustomed to this versatile coding discipline.When Python details for data science When Python data scienceFirst-time coders will understand the basics of programming with Python and then use major tools such as NumPy and Pandas to better organize and process all their data.
From there, mass data analysis begins with training at Data science for beginnersDive deeper into concepts such as data mining, libraries, datasets, and APIs. Here youll also find out how machine learning works and experience using GitHub. This makes it easier for teams to collaborate on the same data without conflict.
That data science path is further deepened by digging into some of the more specialized tools in analyst trading, such as Hadoop, Spark, and Storm to use data faster and more efficiently. ..
Each course in the 2021 Big Data Certified Super Training Bundle costs $ 200 individually, but all 15 courses are now much cheaper to use. Only $ 59.99 and about $ 4 per course..
If youre a little vague about big data and what it means, this package will clear it all
Source link If youre a little vague about big data and what it means, this package will clear it all
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How algorithms are going to change the way you buy and sell stocks – Economic Times
Evolving at a rapid pace, technology is quickly changing the way we trade in the stock market. Especially in the trying times of Covid-19 pandemic, technology has thrown open many opportunities, including a new upcoming generation of traders who are considering trading as a full-time career. One such technology that has revamped stock market trading is algorithmic trading, which has accommodated traders with competitive edge to better their skills and stands poised to outstrip traditional trading methods in future.
Algorithmic trading was introduced and allowed in India in 2008 by the Securities and Exchange Board of India (Sebi). Initially, it started with Direct Market Access (DMA) and was restricted to institutional investors only, but due to the cost advantage and better execution, the trading community welcomed it with open arms. Exchanges has also played an important role in its adoption by offering co-location server 'racks' on lease to broking firms in June 2010, to improve trading speed and align with international markets.
Decoding algorithmic tradingAlgorithmic trading refers to the use of programs and computers to generate and execute (large) orders in markets with electronic access. It generates speed and frequency that is impossible for a manual trader to achieve. Algorithmic trading strategies involve making trading decisions on the basis of pre-set rules that are programmed into a computer. A trader or investor writes code that executes trades on behalf of the trader or investor when specified conditions are met.
The pre-set rules are generally based on timing, price, quantity, or any mathematical model. Apart from profit opportunities for the trader, algo-trading renders markets more liquid and trading more systematic by ruling out the impact of human emotions and errors on trading activities.
Since algorithms are written beforehand and are executed automatically, the main advantage is speed. Besides, it promotes features such as automation, eliminates human intervention and emotions, minimizes slippages, allows flexibility and promotes ease of use, provides extensive data mining and explorations, and safeguards and warning systems against most common human errors.
Also, risk management in algorithmic trading allows setting limits at multiple levels. While some risks associated with technology and capital will still remain, the rewards far outweigh the risks.
The future possibilities of Algo tradingAlgorithms are nothing but a brainchild of human beings. It can work on all possibilities that a human mind can think of. Algo strategies are designed taking into consideration market behavior, including volatilities and uncertain conditions. It is important to understand the strategy and deploy it as per market condition with the help of back-testing and simulation tools. Algo trading allows switching from one strategy to another depending upon market conditions.
With the use of latest technology tools such as artificial intelligence and machine learning, and use of big data, Algo trading is poised to further revolutionize trading. In the developed markets currently, the share of algorithmic trading in volume terms stands around 70-80 per cent, while in India it is approximately at 50 per cent. In the coming years, Algo will capture market share in excess of 95 per cent with volume growing many folds. So the future of trading is Algo and Algo is the future.
(The author is Alternate President at Association of National Exchanges Members of India or ANMI. Views are his own)
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How algorithms are going to change the way you buy and sell stocks - Economic Times
Tech billionaire Alex Karp gives $180k to ousted hermit River Dave – Concord Monitor
Published: 8/19/2021 2:54:55 PM
River Dave will be able to build a new home thanks to an unexpected benefactor: Palantir Technologies CEO and billionaire Alexander Karp, who gave former hermit David Lidstone a personal check for $180,000 last week.
Jodie Gedeon, a kayaker friend of Lidstone, announced the donation on a Facebook group for Lidstones supporters. Gedeon said a lawyer representing Karp delivered the check on Aug. 11. The money will be used to build a new home for Lidstone, after the cabin he built along the Merrimack River burned down weeks ago amid a property dispute.
Lisa Gordon, a Palantir spokesperson speaking on Karps behalf, confirmed the donation but declined to comment further. Karp lives in New Hampshires Grafton County.
How can I express myself and my gratitude towards something like that? I start to tear up whenever I think about it, Lidstone said. For an old logger who always had to work, for anyone to give you that type of money, its incredibly difficult for me to get my head around.
The money will go towards rebuilding elsewhere, Gedeon said. Right now we set up a trust for Dave and its going to be utilized to build him a new home. We have this temporary house set-up for the winter but were not going to be able to build until spring, Gedeon said. She said they are keeping the location of Lidstones winter digs private.
After he was jailed on July 15 for refusing to leave the Canterbury land where he was squatting, Lidstone has received an outpouring of support and offers for help. One potential space for him to rebuild is on a nearby property owned by the congregation of the Concord Friends Meeting.
Karp co-founded data mining company Palantir Technologies in 2003. The company, which received early funding from the CIA and makes software used by governments and businesses, received criticism for working with U.S. Customs and Border Enforcement during the Trump administration. Forbes puts Karps net worth at $2.2 billion.
I truly believe its in Mr. Karps nature to do this, Gedeon said. He is a sincere person cares about others. He has humanity; he does the right thing.
On Saturday, Lidstone and friends will celebrate the donation and his homecoming after his stint at Merrimack County Jail at a party at the home of friend Tom Dunne. The public event will be held at 1 Melvin Mill Road in Warner from 10 a.m. to 5 p.m.
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Tech billionaire Alex Karp gives $180k to ousted hermit River Dave - Concord Monitor
IoT Analytics Market Size to Reach USD 58.4 Billion by 2025 at 30.9% CAGR – GlobeNewswire
New York, US, Aug. 18, 2021 (GLOBE NEWSWIRE) -- Market Overview: According to a comprehensive research report by Market Research Future (MRFR), Global IoT Analytics Market information by Deployment, by Components, by Analytics Type and Region forecast to 2025 market has been esteemed at USD 9.1 billion in 2018 and required to develop at a CAGR of 30.9% by 2025, to arrive at USD 58.4 billion by 2025.
IoT Analytics Market Scope: The global IoT analytics market is witnessing vast demand. The rising demand for simple-to-use AI capabilities to get more value from IoT data drives the market growth hugely. IoT analytics infrastructures help in making sense of collected data. IoT analytics also takes care of harvesting and processing massive data volumes, data mining and building ML solutions by involving data storage capacities for structured and unstructured data.
Rising uses of instant ML technology and industrial IoT as a service solution to leverage IoT data and generate new insights without the need for complex model training and management create a substantial demand for IoT analytics. With advancements in technologies and digitization, there is a growing need to have IoT analytics platforms incorporated into every business system.A large number of manufacturing companies have already embraced industry 4.0 regulations, which define the growing landscape of IoT analytics.
Dominant Key Players on IoT Analytics Market Covered Are:
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Market USP Exclusively Encompassed:IoT Analytics Market DriversIoT technology is being increasingly implemented into complex industrial environments as part of digital transformation strategies. Manufacturing sectors' efforts to increase productivity across the value chain by streamlining operational efficiencies impact market growth positively. Additionally, rapid developments in industrial IoT solution environments, data analytics at the edge, remote health care, and robotics are major trends boosting the market size.
Domains such as facility remote monitoring, digital health, and connected, smart environments would continue to develop due to social distancing and health requirements. This, as a result, would benefit the IoT analytics market, ushering in greater human augmentation in work.
Connected devices would continue to define numerous industries in the coming year as basic health-and-safety needs as COVID-19 continues to take center stage. Furthermore, data-intensive experiences that IoT devices like self-driving cars and wearable devices are other trends projected to continue to garner momentum, fueling IoT's prominence.
With the COVID-19 crises expected to extend beyond 2021 and social distancing requirements bolstering remote work, the need for distributed computing resources close to devices and users and away from centralized locations such as the office, a data center and the cloud would be increased. These edge resources away from centralized clouds, particularly as employees continue to work from home, patients use digital health resources, and factories use more remote monitoring and automation.
Browse In-depth Market Research Report (141 Pages) on IoT Analytics Market:https://www.marketresearchfuture.com/reports/iot-analytics-market-1757
Segmentation of Market Covered in the Research:The IoT analytics market is segmented into analytics types, components, deployments, applications, organization size, industry verticals, and region. The analytics type segment is sub-segmented into predictive analytics, prescriptive analytics, and descriptive analytics. The component segment is sub-segmented into software and services.
The deployment segment is sub-segmented into on-premise and on-cloud. The application segment is sub-segmented into energy management, predictive maintenance & asset management, inventory management, security & emergency management, and others.
The organization size segment is sub-segmented into large enterprises and SMEs. The industry vertical segment is sub-segmented into manufacturing, retail & eCommerce, government & defense, healthcare & life sciences, energy & utilities, and others. The region segment is sub-segmented into Asia Pacific, Americas, Europe, and rest-of-the-world.
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Regional AnalysisNorth America is estimated to continue to dominate the global IoT Analytics market. The strong presence of major IoT analytics providers, alongside the proliferation of 5G, IoT technology, IoT analytics sensors, and IoT analytics security privacy, would drive the growth of the market in the region. Besides, increased demand for IoT analytics from major industry verticals and highly reliable Internet connectivity in this region would boost the market growth.
Europe is the second-largest market for IoT analytics. The market growth is driven by the rising adoption of 5G-enabled IoT systems across the manufacturing sector. Additionally, the rapid adoption of smart connected devices and the presence of key technology providers contribute to the market growth in the region.Also, substantial R&D investments to advance IoT infrastructure and essential network connectivityinfrastructure propel the regional market growth. Vast developments in the automotive sector, such as driverless vehicles, advanced driver assistance systems (ADAS), boost the market demand.
Asia Pacific has emerged as a profitable market for IoT analytics solutions globally. High R&D investment and increasing focus on improving internet connectivity in the region are key factors estimated to influence market growth.
Furthermore, factors such as technical expertise, the strong presence of key players, and increased industrialization would foster the market's growth. Moreover, the rising demand for IoT Analytics services in emerging countries such as South Korea and Japan is likely to boost the region's IoT Analytics market share during the assessment period.
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COVID-19 Impact on the Global IoT Analytics MarketThe COVID-19 outbreak has impacted IoT analytics positively. The pandemic fostered automation, digitization, and industrial internet of things (IIoT), needing robust IoT analytics to counter increasingly complex opportunities. The IoT analytics market witnessed a constant uptick over the past few months. Besides, technology providers are making substantial investments to foster R&D activities to improve IoT services.
In 2021, the market is expected to witness continual growth due to the major emphasis on developing more comprehensive technologies. Many organizations would prioritize investments in IoT analytics due to stricter data privacy laws for consumer protection that regulatory bodies would impose beyond 2021. This would also boost investments in confidential computing, the virtual private cloud, and other security infrastructure.
Competitive Analysis:The IoT analytics market is expected to witness significant product launches and several strategic approaches, such as expansion, collaboration, mergers & acquisitions, and product launches. Mature industry players also make significant investments in research and development activities and expansions.
For instance, recently, on April 9, 2021, Glassbeam announced its partnership with Deloitte to meet the most urgent business needs of customers in the healthcare IoT analytics sector. This strategic ecosystem relationship is expected to drive rapid change in the healthcare IoT analytics sector, helping caregiving organizations to gain a higher return on assets.
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IoT Analytics Market Size to Reach USD 58.4 Billion by 2025 at 30.9% CAGR - GlobeNewswire
5 mins with… Mark Day, iRhythm – Healthcare Global – Healthcare News, Magazine and Website
Mark Day is Executive Vice President of Research & Development at iRhythmTechnologies, a company that has developed an FDA-cleared deep-learning algorithm for classifying diverse heart rhythms. We caught up with Mark who told us why he believes AI and human intelligence is the best combination for improving healthcare.
In which areas of healthcare is AI making the biggest difference already?AI is revolutionising healthcare in areas where data drives clinical insight. This dynamic is particularly prevalent in diagnostics, where medical imaging was the first area to be transformed by AI, due to an initial focus of AI research on image analysis. More recently, AI has rapidly gained adoption in everything from drug discovery to iRhythms focus area, ambulatory cardiology monitoring.
For years, clunky Holter monitors have been used for arrhythmia monitoring. These monitors have low patient compliance and are woefully inadequate in identifying, diagnosing, and managing the most common and deadly arrhythmias.
Now, new innovations on the market are redefining how cardiac arrhythmias can be clinically diagnosed by combining wearable biosensing technology with cloud-based data analytics and AI-based algorithms to bring dependable and easy remote monitoring to the wider population.
How can AI be used to improve diagnosis and screening for cardiac diseases?AI brings accuracy and efficiency gains for patients and providers at scale. Often, an arrhythmia causing patients symptoms can be as short as four heart beats, or even two beats in a case where extended time between them is considered a clinical pause. Given that a typical heart beats 1.5 million times in two weeks, finding these significant events is a needle in a haystack kind of problem perfectly suited for AI.
iRhythm, for example, has collected over 750 million hours of curated heartbeat data, creating the largest repository of labelled ECG patient data in the world. This allows for expanded training of deep-learned algorithms across a larger database, resulting in enhanced diagnostic accuracy and better quality assurance.
Can AI help patients take greater control of their own health?AI is transforming the delivery of care, and therefore enhancing patients' entire healthcare experience. Wearables, for example, play a critical role for patients looking to take care into their own hands. AI technology allows wearables to improve diagnostic insight without sacrificing convenience. When patients have tools to continuously monitor their health, they're able to better manage their conditions and own aspects of their healthcare journey.
What steps can be taken to prevent bias in AI?To be clear, bias in AI comes from the data used to teach an algorithm, not from the technology itself. Training data needs to be clean and free of bias. AI researchers should work to ensure datasets are both reflective of the intended population and that they were collected in a manner untainted by bias.
Where do you predict AI will have the greatest impact next?To date, most AI healthcare solutions have delivered value by analysing collected data, which is to say by providing insight into the past. Prediction of the future will be the next frontier of AI.
In healthcare, a key problem is determining who is at risk so prevention can be used to limit illness. Data mining patients EHR records alone will not suffice rather, assessing all possible elements to identify whos at risk of a serious health event and ensuring identified patients get the proper preventative medical care before that can happen.
AI is an incredibly powerful tool to sift through expansive datasets and uncover previously hidden relationships. For example, previous conditions, genetics, drug use, if theyve had an ECG, if theyve had Covid-19, and everything else in between can be used by AI to identify risk and inform prediction.Predictive AI will be transformational the ability to take disparate data and have AI identify trends and anticipate outcomes will change the trajectory of our lives.
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5 mins with... Mark Day, iRhythm - Healthcare Global - Healthcare News, Magazine and Website
The Legal Regulations And Perspectives Of Cryptocurrency In Kazakhstan: Opportunities Of The Astana International Financial Centre For Chinese Crypto…
In light of the sudden changes in the crypto mining situation inKazakhstan with the restrictions on Bitcoin computational processesby the Chinese government that escalated into the recent strictmeasures implemented in June 2021, Kazakhstan's bitcoin mininghas dramatically surged into third place on the global market.
In order to further its advantage on the global mining market,Kazakhstan has started its actions towards the creation of relativeadvantages in mining conditions while also maintaining closecontrol of the situation.
In this article, we would like to describe the recentdevelopments in the legislation of the Republic of Kazakhstan onthe matters of cryptocurrency and digital mining, as well as toshed the light on the opportunities of registering in the AstanaInternational Financial Centre ("AIFC") for foreigncrypto miners.
It is important to draw your attention that the legal regulationof cryptocurrency and digital mining is still in the process ofdevelopment in the Republic of Kazakhstan, and this article as ofthe date of publication is solely based on the recent developmentsand current legislation of the Republic of Kazakhstan.
1.1. The AIFC as an international hub for development of thedigital asset market
The AIFC is a financial hub located in the Republic of aKazakhstan. It is a special territory defined by the ConstitutionalStatute of the Republic of Kazakhstan. The main objective of theAIFC is to ensure a friendly ecosystem for foreign investments andsecure independent regulation. This special territory operates onCommon law framework secured by the independent Court headed byChief Judge Lord Mance and other British judges.
Since its establishment in 2017, the AIFC became a centre ofattraction for crypto mining companies, which was facilitated by anofficial legalization in 2020. For instance, such large players asBitfury, Powerry, Minebest and others registered their legalentities in the AIFC jurisdiction to guarantee the Rule of Law.
1.2. Climate
Kazakhstan possesses a considerable amount of cheap electricityin Central, Northern and North-Western regions and has a sharplycontinental climate characterized by a cold and windy weather,which are one of the main fundamental conditions for data centersand mining farms operation.
Miners have an opportunity of benefitting from favorable weatherconditions, cheap electricity and legal status by opening legalentity in the AIFC and operating data centers in Kazakhstan orcontracting mining hotels for hosting.
1.3. Legal status
In July 2020, Kazakhstan officially recognized Bitcoin as adigital asset that could be accounted as any other commodity. TheAIFC Fintech rules allow establishment of crypto exchanges andbuilding other regulated activities based on digital assets.
1.4. Developments in the regulatory regimes for digitalassets and mining
The significant improvements in Kazakhstani regulatory regimesfor mining and digital assets were achieved. As such, thelegislation of the Republic of Kazakhstan established a legalregime for mining and cryptocurrency. To date, there are 17 miningfarms that currently officially operate in the territory ofKazakhstan.
At present, the Ministry of Digital Development, Innovation andAerospace Industry of the Republic of Kazakhstan together with theAIFC and the Kazakhstan Association of Blockchain and Data CenterIndustry are in the stage of drafting the blockchain technologiesand crypto industry regulations that would allow to achieve thesmooth operation of crypto exchanges in the AIFC territory.
In addition, due to the increased demand from mining companies,in 2021, certain amendments to the Tax Code were presented with theintroduction of a tax for digital mining in the amount of 1 tenge(0.00232 USD) per 1 kW/h from January 1, 2022. This legislativedecision should not be interpreted as an obstacle for the newminers migration to Kazakhstan, but rather as another step towardslegalization of crypto mining and data centers (mining farms),which is considered as a necessary measure taking intoconsideration the restrictive control over miners around theworld.
As such, in order to obtain a special permit or license to carryout digital mining in the Republic of Kazakhstan, the following hasbeen established:
To point out, Kazakhstani legislation does not have any rules orrestrictions governing operations with hash rates. Therefore,operations with hash rates are legal in Kazakhstan.
However, please kindly note that Kazakhstani legislationcharacterizes cryptocurrency as a form of property, not a financialinstrument or means of payment. The Kazakhstani law prohibits theissue and circulation of cryptocurrency in Kazakhstan.
1.5. IT park Astana Hub for Bitcoin miningactivities
The AIFC has established the IT park for Bitcoin miningactivities providing 0% tax regime (CIT, VAT, salary taxes 0%)fordata centers who registers and resides in the IT park Astana Hubunder the premises of the AIFC (only royalty of 1% of the annualturnovers has to be paid).
1.6. Aspects of electricity price and the percentage of cleanenergy
While establishing a legal status to data mining is a crucialand vital element for attraction of new investors, the lowelectricity prices in Kazakhstan areone of the mostsignificant factorsin this regard.
Since cryptocurrency mining farms consume considerable amountsof electricity and bitcoin mining rewards decreased by 50 percentin May 2020, finding cheap sources of power is particularlyessential. Besides being cheap, Kazakhstan's electricity pricesare not subject to high volatility and mostly remain stable duringthe year in comparison to prices in China that are subject toregular seasonal changes.
Uninterrupted availability of electricity in Kazakhstan is alsoanother reason that makes it one of the most appealing destinationsfor data mining. Consequently, one of the world's biggestmining centers managed by Enegixcompany is planned tobe opened inEkibastuz, Kazakhstan.
To date, there are 116 power facilities that produce renewableenergy in the Republic of Kazakhstan, with an installed capacity of1685 MW, which accounts for 3% of the total electricityproduced.Since there is no need for electricitytransportation and storage, most electricity consumption comes fromthe mining industry allowing to rapidly develop theindustry.Construction regulations and experienced contractorscan assist miners to set up a turnkey mining farms within 3-4weeks.
Kazakhstan intends to increase the share of renewable energy intotal electricity production to 6% in 2025, to 10% by 2030, and by2050, alternative and renewable energy sources should account forat least half of all energy consumption according toKazakhstan's obligations on Low-carbon and Climate-sustainableDevelopment under the Paris Agreement. At present, around 20% ofenergy is a natural gas, which is cleaner than coal, since gasmainly is a by-product of oil extraction.
Furthermore, apart from 0% tax regime for crypto miners and amild construction regime for mining farms construction, Kazakhstanhas a very reliable power grid system operating on several reservesources of energy.
1.7. Opportunities for Chinese crypto miners
The Chinese authorities prohibit crypto miners to make exodusfrom China, but Chinese miners often inquire our Team onregistration and relocation issues in the AIFC. There are severallisted mining firms that are already operating and could be checkedthrough the economic activity codes of the registered legalentities: 62032 information and communication equipmentmanagement activities, 63111 hostings and relatedactivities.
1.8. Government support
Although this new field has generally been welcomed, the noveltyof the industry as well as the lack of a clear and determinedregulatory environment led to uncertainty within some governmentagencies towards security and viability of the cryptocurrencymarket.
However, nonetheless, the recent developments inKazakhstan's crypto industry proved otherwise, and as wasindicated earlier, in 2020, the new amendments to the legislationof legitimized mining and digital technologies wereestablished.Suchkey definitions as"cryptocurrency", "digitalasset", and "digital mining" were alsoinitiated into the Law of the Republic of Kazakhstan "OnInformatization".In addition, this Law stipulatesthat onlyasset-backed cryptocurrencies can legally operate inKazakhstan, except in cases that will be introducedlater.Therefore,although unsecured cryptocurrencies arenot officially legal, it is still not clear whether the governmentwill impose a complete ban on unbacked digital currencies such asBitcoin.
In general,the current developments signals the interestof Kazakhstan in this industry, which could be seen intheestablishment ofthenewlegal regulationthat provides a clearer legal framework for the circulation andoperation of digital assets and legitimized mining. As part of thevision of Kazakhstani government, this was initiated with theaim of attracting high-tech industry investments for promotion ofeconomic growth and diversification.
1.9. Bank Accounts for Cryptocurrencyin Kazakhstan
The Kazakhstan Association of Blockchain and Data CenterIndustry informed that crypto exchanges registered in the AIFCmight shortly start operating with local banks which would allowtheir clients to openly and officially work with cryptocurrency.Such an opportunity is planned to be realized after the launch ofthe pilot project of the AIFC with second-tier banks.
According to the intended outline, in order to get on the cryptoexchange, an investor is required to be the legal account'sowner in one of the banks registered with the AIFC. From thisaccount, the entrepreneur will have the opportunity to buy acryptocurrency, transfer money, and carry out various operationswith it on the exchange market.
The AIFC pilot project is estimated to last for one year for thepurposes of Kazakhstani government to assess and evaluate thebenefits and risks of digital assets. Although the circulation ofdigital currency in Kazakhstan is currently prohibited, it isprojected that the ban on cryptocurrency in Kazakhstan might becomeless categorical or might even be cancelled after the successfulcompletion of the pilot project.
1.10. Kazakhstan doubles mininginvestment1
Kazakhstan is planning to double its digital currency mininginvestment, and is continuing to develop its central bank digitalcurrency (CBDC). The feasibility and opportunity of introduction ofthe CBDC tenge by the Central Bank of Kazakhstan is currently beingdemonstrated, and the AIFC intends to assist in a trial andestablishment of a legitimate ground for Kazakhstan to implementits digital currency.
The AIFC's covenant includes smart contract, cryptocategorizations, and digital wallets. Kazakhstan earlier hasalready developed a way to store cryptocurrency and distribute itto normalize the procedures via a proficient platform. In June2020, Kazakhstan adopted a development plan for blockchain anddigital technology.
We believe that our specialists' experience and knowledgemay be of great help to the organisations that are planning toregister in the AIFC. The registration of the company in the AIFCtakes about 3-5 business days upon the preparation and receipt ofall necessary documents.
ServicesOur team has an extensive experience in provision of legal serviceson the registration of a company in the Astana InternationalFinancial Centre (AIFC), including all post-registrationservices.Once the company is registered, we will be happy to act as a legalcounsel in connection to its ongoing activities in the Republic ofKazakhstan. Contracting for hosting could also be done with theassistance of our Team through the AIFC, which operates as a"one stop shop" for foreign investors.About GRATA International
GRATA International is the largest independent Kazakhstani lawfirm, and one of the leading law firms in Central Asia and theCaspian Region. GRATA has provided a wide range of legal servicesin these regions for almost 30 years.
250 professionals in 19 countries advise major international andlocal ?rms, funds, banks, insurance ?rms, construction companies,mining and crypto mining companies, airlines, light and heavyindustry companies, telecoms, pharmaceuticals and others.
GRATA International is recognized as one of the leading law ?rmsin all jurisdictions where it operates by major international legalranking agencies: The Legal 500, Chambers Global, ChambersAsiaPaci?c, IFLR1000, Who's Who Legal, Asialaw Pro?les andaward of China Business Law Journal.
Footnote
The content of this article is intended to provide a generalguide to the subject matter. Specialist advice should be soughtabout your specific circumstances.
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How Veterans Affairs is helping to lead the way on prostate cancer research – Federal News Network
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Prostate cancer is the most common type of cancer among Americas veterans population. An estimated 500,000 veterans are living with a prostate cancer diagnosis today. So it makes sense that the Veterans Health Administration would make prostate cancer research a priority. One of the latest developments is a partnership with the Prostate Cancer Foundation. Among other things, its helped to fund research into precision oncology treatments that are tailored to each patients specific physiology. Dr. Matt Rettig is the chief oncologist at the VA of Greater Los Angeles. He joined Federal Drive with Tom Temin to talk about some of the research questions VAs trying to answer.
Dr. Matt Rettig: Prostate cancer is the most commonly diagnosed major malignancy amongst veterans. In fact, its the most common major malignancy amongst males in the general US population, with somewhere around 200,000-250,000 new cases per year. Currently, there are approximately 500,000 veterans who are alive with a diagnosis of prostate cancer, and about 16,000 to 17,000 of them who have the most advanced stage of the disease, that is called metastatic prostate cancer, meaning its spread beyond the prostate to another organ. So its a big problem. Its associated with a lot of complications, what we call morbidity, as well as unfortunately, mortality. And so its a high priority malignancy for the VA so that we can better understand it and better treat it for our veterans.
Jared Serbu: As far as we know nothing specific about the veterans population per se, other than it tends to be older. So it is the rate of prostate cancer in the veterans population general reflective of what youd see in the same age groups in the general population?
Dr. Matt Rettig: It is similar, there are some important questions that need to be addressed. One is the role of Agent Orange. So Vietnam veterans whove had boots in the ground on in Vietnam War are considered to be exposed to Agent Orange, which is a service connected disease, prostate cancer associated with Agent Orange. In addition, the VA population is over represented by certain minorities, most notably African Americans as compared to the general population. And African Americans have a higher incidence of prostate cancer. And thats true in the VA system, as well as a higher mortality rate in the general population. Its not clear that theres a major difference in mortality in the veteran population. One of the major factors that results in health disparity between African Americans and Caucasians is access to care. And that is a factor that is minimized within the VA system. And in fact, many treatments that are used for prostate cancer patients, especially advanced prostate cancer patients are more effective in African Americans than Caucasians.
Jared Serbu: Interesting. So you mentioned Agent Orange is one question, what are some of the other big research questions around prostate cancer that VA is working on specifically right now?
Dr. Matt Rettig: Yeah, so prostate cancer is a major area of focus of research. And when we think about research, we think of laboratory or bench research, and clinical research, and something in between, which is called translational research, which bridges the divide between the lab and the clinic. And all three of those types of research are ongoing at the VA. Some of the big questions that we need to answer is what is the role of certain environmental exposures? Agent Orange is a good example. In the biology, the aggressiveness of prostate cancer, does it result in a different version of prostate cancer thats more aggressive, that has different genetic findings associated with it? And thats an important question thats ongoing, and then hopefully will be answered in the near future. Along those lines, we also want to know if patients who have Agent Orange is associated prostate cancer have a different response to therapy? also an important question thats ongoing, and something thats being addressed in a number of clinical trials, including some that I am conducting. Another big question is whether or not we can use the patients genetic background, the specifics of the patients tumor, the genetics that are unique to the patients tumor, in order to select the right treatment for the right patient. So historically, using drugs for cancers, including prostate cancer, has been kind of the throw the spaghetti at the wall approach where one size fits all And clearly, thats not the ideal approach. We want drugs that are going to have a higher likelihood of working in an individual patient. And knowing the specifics of the patients tumor is really critical in order to make that happen. And we do that by performing genetic sequencing on the tumor, and are able to pair a specific genetic mutation with a specific therapy. Thats not done in all patients. That is the sequencing is done. But its not all patients that have a mutation that can be paired with a specific drug. But the number of genetic changes that can be paired with a specific drug is increasing. And hopefully, we have well have a drug for it for every specific mutation in the relatively near future.
Jared Serbu: And that that whole concept youre just talking about, I think, falls in the bucket of whats sometimes called precision oncology, right? You mentioned genetic sequencing is a big part of that. But are there other factors that you look at to help tailor that treatment to a particular individual beyond the genetic sequencing?
Dr. Matt Rettig: Yeah, so thats, thats exactly right. So precision oncology is basically using patient specific features and characteristics that allow the selection of a specific therapy, a drug that is most likely to work. Now, the genetics is really the driver of precision oncology. But there are non-genetic, what we call biomarkers, factors, that can be used to select patients for therapy, including fairly straightforward clinical factors. So, for example, we know that African Americans respond to a specific type of vaccine much better than Caucasians. And the difference is quite striking. So just by having an African ancestry, one is more likely to respond to this particular treatment. So we use clinical factors that are also whats called imaging biomarkers where we have state of the art PET scans that can tell us what the patients prostate cancer is like, does it express a specific protein that can be targeted for therapy, and those are coming online. The scans have been now FDA approved. And theres therapies that are going to be imminently approved, based upon certain imaging biomarkers and imaging characteristics. So the list goes on and on. But genetics is the main driver, but other factors are used to select the right drug for the right patient.
Jared Serbu: And how mature is this whole concept of precision oncology in the prostate cancer space? Do we have any way to quantify how much more clinically effective it is than the throw the spaghetti against the wall approach that you mentioned?
Dr. Matt Rettig: Yeah, so its still in its relatively early days. So the technology to identify the genetic mutations is fairly mature. And the VA will do that on any patient with advanced cancer. In fact, not just prostate cancer, any cancer. The proportion of patients who have a mutation that would qualify them for a precision treatment varies from cancer to cancer. So about a third of all prostate cancer patients with advanced disease. The question is, really, can we get the sequencing done on a national level, so that theres no veteran thats left behind the VA is a huge integrated healthcare system. Of course, its the largest integrated health care system in the United States, there are over 150 different VA medical centers, and that doesnt include all of the outpatient clinics. And as a consequence, there is variability in the knowledge base and the resources that an individual VA may have. So what we want to do as part of the precision oncology program is to provide care to veterans, irrespective of their geography, we have another number of programs that have been initiated to achieve that. So veteran doesnt have to be at one of the main academic VA medical centers in order to achieve precision care. And so thats a really important feature of of the precision oncology program in prostate cancer, so that we can democratize precision oncology amongst all of our veterans. This project of precision oncology in prostate cancer has been going on since 2018. It was a key strategic partnership that the VA has started between the VA and the Prostate Cancer Foundation, which is the largest philanthropic institution in the United States in the world, for that matter for prostate cancer research and the prostate cancer. foundation initially funded this with $50 million. So its an incredible gift that the VA has received. And the VA has now expanded on this so that the program can reach more and more veterans.
Jared Serbu: And I assume one of the functions of that partnership would be to help export any anything that youve learned in the VA setting to the broader health communities. That a fair assessment?
Dr. Matt Rettig: Yes, absolutely. So the VA hasnt has incredible resources in terms of data mining, a huge population of veterans. And when we put databases together, we dont want to keep it just for ourselves. We want to make it accessible to researchers in the academic community who might not be at a VA so that we can learn the most from the the data and the patients that we do have.
Jared Serbu: Last thing I wanted to get to before we run out of time here is a specific clinical trial that I know you designed and worked on, where I think youre taking some of the drug therapies, or at least one drug therapy thats common for prostate cancer and trying to see if its effective in COVID-19 patients. Im gonna let you pronounce the drug for us, but tell us what what questions youve been trying to answer through that trial.
Dr. Matt Rettig: Yeah, so this was a study that we initiated last year, towards the height of COVID. Of course, were having a resurgence, at this time, at least in in many states. And we were looking for a novel way of treating COVID with an existing FDA approved drug, drug obviously wasnt approved for COVID, but can be repurposed for the treatment of severe COVID. So we tested a prostate cancer drug thats commonly used as a hormone therapy called Degarelix. And what it does is it temporarily suppresses male hormone levels. And the rationale for this testing this type of therapy amongst COVID patients was related to the mechanism, the manner in which the virus enters human cells, the target cells, for example, on the lining of the lungs. Well, there was a study published in March of last year, a landmark study, which demonstrated that the virus uses two key proteins on the surface of cells to gain entry, its like the the door that it needs to open in order to get into cells. And these two proteins, the names dont matter, but one is called ACE2, and the other ones called TMPRSS2, are well known if youre in the field of prostate cancer, because we know that theyre tightly regulated by male hormones. So male hormones cause more of these proteins, this door that the virus uses to get into cells to be expressed or present on the surface of the cells that are targeted by COVID. So the idea is that if we can temporarily suppress male hormones, and we would lower the amount of these proteins, this doorway to entry of the virus into the into the target cell, and thereby effectively treat severe COVID. So we can conducted this study., and it turns out, we were able to do it very, very rapidly, because we were using the clinical trials infrastructure of the precision oncology program, which was already in place, but was kind of on semi hold during COVID. So the infrastructure was already there. The VA rapidly funded the study, the study was completed and of course we were waiting for the results. It was a double blind study. And as the lead investigator, Im not allowed to know what the results are until theyre completed. So this is something that were waiting for. There has been a study that was conducted with a similar drug in Brazil, which was published, which showed very, very striking reduction in the duration of hospitalization, and importantly, mortality of hospitalized patients with COVID. Thats in Brazil, its a different population. They have different resources in that country as compared to the United States. But it was an interesting merging of prostate cancer and COVID-19 knowledge into a clinical trial.
Jared Serbu: That is super interesting. Im just curious on one last thing, by reducing those number of doorways on a cell surface, is the thinking that you can reduce the spread of virus throughout the body or really primarily in critical tissues like lung tissue.
Dr. Matt Rettig: Yeah, it really depends on whether or not the receptors that these doorways are regulated by male hormones on all tissues. We do see that they are regulated by male hormones in the main site of infection, which is the lining of the lungs in the respiratory system, the nasal cavity, the oropharynx As well as other important structures such as the heart. Some of the organs, we dont know the regulation of. So some of its a little bit unknown, but the main source of the virus entering cells is the lung, and we do know that the lung uses male hormones to induce the expression of these doorways, these proteins that the virus uses.
Read more:
How Veterans Affairs is helping to lead the way on prostate cancer research - Federal News Network
Intrusion (INTZ) falls 1.19% in Light Trading on August 20 – Equities.com
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INTZ - Market Data & News
Today, Intrusion Inc Incs (NASDAQ: INTZ) stock fell $0.05, accounting for a 1.19% decrease. Intrusion opened at $4.16 before trading between $4.34 and $4.08 throughout Fridays session. The activity saw Intrusions market cap fall to $73,141,700 on 196,276 shares -below their 30-day average of 4,590,594.
NTRUSION, Inc. is a global provider of entity identification, high speed data mining, cybercrime and advanced persistent threat detection solutions. INTRUSIONs family of solutions includes Shield, a combination of plug-n-play hardware, software, global data, and real-time Artificial Intelligence (AI) services that provide organizations with the most robust cybersecurity defense possible, TraceCop for identity discovery and disclosure, and Savant for network data mining and advanced persistent threat detection. INTRUSIONs solutions help protect critical information assets by quickly detecting, protecting, analyzing and reporting attacks or misuse of classified, private and regulated information for government and enterprise networks.
Visit Intrusion Inc's profile for more information.
The Nasdaq Stock Market is a global leader in trading data and services, and equities and options listing. Nasdaq is the world's leading exchange for options volume and is home to the five largest US companies - Apple, Microsoft, Amazon, Alphabet and Facebook.
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Intrusion (INTZ) falls 1.19% in Light Trading on August 20 - Equities.com
Investors in Griffin Mining (LON:GFM) have made a solid return of 137% over the past five years – Yahoo Eurosport UK
The last three months have been tough on Griffin Mining Limited (LON:GFM) shareholders, who have seen the share price decline a rather worrying 33%. But in stark contrast, the returns over the last half decade have impressed. In fact, the share price is 137% higher today. We think it's more important to dwell on the long term returns than the short term returns. Ultimately business performance will determine whether the stock price continues the positive long term trend.
Now it's worth having a look at the company's fundamentals too, because that will help us determine if the long term shareholder return has matched the performance of the underlying business.
View our latest analysis for Griffin Mining
There is no denying that markets are sometimes efficient, but prices do not always reflect underlying business performance. One imperfect but simple way to consider how the market perception of a company has shifted is to compare the change in the earnings per share (EPS) with the share price movement.
During the last half decade, Griffin Mining became profitable. Sometimes, the start of profitability is a major inflection point that can signal fast earnings growth to come, which in turn justifies very strong share price gains.
The graphic below depicts how EPS has changed over time (unveil the exact values by clicking on the image).
earnings-per-share-growth
We know that Griffin Mining has improved its bottom line lately, but is it going to grow revenue? This free report showing analyst revenue forecasts should help you figure out if the EPS growth can be sustained.
It's good to see that Griffin Mining has rewarded shareholders with a total shareholder return of 53% in the last twelve months. Since the one-year TSR is better than the five-year TSR (the latter coming in at 19% per year), it would seem that the stock's performance has improved in recent times. Given the share price momentum remains strong, it might be worth taking a closer look at the stock, lest you miss an opportunity. I find it very interesting to look at share price over the long term as a proxy for business performance. But to truly gain insight, we need to consider other information, too. For example, we've discovered 2 warning signs for Griffin Mining (1 is significant!) that you should be aware of before investing here.
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But note: Griffin Mining may not be the best stock to buy. So take a peek at this free list of interesting companies with past earnings growth (and further growth forecast).
Please note, the market returns quoted in this article reflect the market weighted average returns of stocks that currently trade on GB exchanges.
This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.
Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team (at) simplywallst.com.
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