Category Archives: Decentralization
The Meaning of Community in Crypto Discussed at Consensus 2023 – Yahoo Finance
Do users actually care whats under the hood of an app?
Cryptocurrencies censorship resistance and global reach have been the main value proposition of this technology for people not interested in sheer speculation. However, just the existence of technology is not enough: for it to really spread, empower and benefit those who need it most, there has to be infrastructure, products and services that will turn a shiny concept into the actual reality of peoples lives.
This article is excerpted from CoinDesks inaugural Consensus @ Consensus Report, the product of intimate, curated group discussions that took place at Consensus 2023. Click here to download the full report.
Grassroot adoption is all about making sure you target everyday people, Tricia Wang, co-founder of the Crypto Research and Design Labs (CRADL), said during the interactive session Grassroots Innovation: Realizing Cryptos Empowerment Promise for Social Inclusion at Consensus 2023.
See also: What Kind of Culture Are We Building in Web3? | Opinion
Further, sometimes crypto developers will have to be obsessively pragmatic, meaning they are culturally attuned to solutions that may work for one group of users but not another, rather than being dogmatic about cryptos highfalutin ideals.
What are the winning design principles founders should focus on if they want to meaningfully impact users lives?
Should builders prioritize scaling their products as broadly as possible or helping users understand how the product works to the maximum possible extent?
Should crypto and blockchain integration be explicit or stay under the hood?
Should decentralization be immediate or take place over time?
A range of considerations goes into these choices
Click here to download the full Consensus @ Consensus report.
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The Meaning of Community in Crypto Discussed at Consensus 2023 - Yahoo Finance
Expedite the Action Plan for Reconciliation – President – Newsfirst.lk
President Ranil Wickremesinghe convened a discussion at the Presidential Secretariat yesterday afternoon (08) to address the Action Plan for Reconciliation. During the meeting, the President instructed the relevant departments to expedite the drafting of legislation necessary for the plans implementation.
The progress of initiatives within five key areas -legislation, institutional activities, land issues, prisoner release, and power decentralization, was also reviewed.
The discussion encompassed several important topics. The implementation of the Truth and Reconciliation Commission (TRC), the establishment of a National Land Council, and the formulation of a National Land Policy were among the matters addressed.
Additionally, the President emphasized the need for enhanced operations of the Office of Missing Persons, including digitization efforts and the issuance of Certificates of Absence for individuals who had previously disappeared without trace.
Furthermore, President Wickremesinghe instructed the relevant parties to complete the ongoing initiatives to establish the Office of Reparations and the Office for National Unity and Reconciliation within the next two to three months. A comprehensive report on the progress of these programs was also requested.
Regarding land-related issues, particular attention was given to resolving problems associated with displaced persons resettlement, releasing privately held lands for public use, and addressing Mahaweli lands concerns. The President emphasized the urgency of taking immediate action to settle these land-related issues and tasked the officials with devising effective mechanisms for their resolution.
To address the release of prisoners and amnesty matters, the President instructed the relevant officials to submit a detailed report through the Ministry of Justice.
The discussion also covered topics such as power decentralization, provincial-level development plans, and the appointment of a Provincial Ombudsman. These matters were thoroughly deliberated upon to ensure effective governance and progress at the provincial level.
PMD
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Expedite the Action Plan for Reconciliation - President - Newsfirst.lk
Crypto Woes – Inkstick – Inkstick
The latest breach in crypto in the wild fleeting hope that another does not happen before this is published is the attack on Tornado Cash. The attacker took over the decentralized autonomous organizations platform and gained access to reroute transactions. Ignoring all the things wrong with Tornado like the fact that it was blacklisted for allowing hackers to launder $7 billion the attack is a reminder of the high stakes and low standards of security in the crypto ecosystem.
In May alone which was a quiet month for crypto hacks at least $14.1 million was lost to three attacks on major crypto platforms. DAI, which was responsible for $6.5 million of that figure, was hacked for the third time since its inception. In April, $12.5 million was lost, according to Rekt, which tracks breaches and incidents in the crypto ecosystem.
In the first quarter of 2023, at least $370 million was lost and even that is a record low in comparison to the $5 billion lost in the last quarter of 2022. The global cryptocurrency market was valued at $4.67 billion in 2022 and is expected to expand at a compound annual growth rate of 12.5% from 2023 to 2030, according to Grandview Research.
Most of cryptos growth has been fueled by the promise of investing in the worlds next financial system and for a number of benefits over the traditional financial system. Transactions and the inherent value of cryptocurrencies are controlled by the general public instead of a central authority, such as a bank. The promise is that since it gives the public the power that is often vested in governments, it is much more private, and ironically, more secure. Crypto bros and investors tout that it is the future of money.
In fact, the entire premise of what is called Web3 a generation of open-source and interconnected decentralized applications powered by blockchain architecture, which is also touted as the future of the internet is based on the tenets of decentralizing authority and offering more privacy, and security.
SECURITY WOES
Crypto wants to be the worlds next money, but it is a security nightmare. Despite the allure of decentralization and anonymity, the world of cryptocurrency remains plagued by significant security vulnerabilities.
The scale of cryptocurrency breaches is alarming. These breaches expose the vulnerabilities present in exchange platforms, wallets, and even smart contracts. Sophisticated phishing attacks, malware, and insider threats further exacerbate the risks faced by crypto users.
And the fallout of these hacks is devastating. Apart from the fact that many of these incidents lead to assets being moved from the accounts of legitimate users, they also lead to a crash in the value of the main cryptocurrencies of the platform affected, wiping out millions sometimes billions in market value.
I just woke up one day and my money was gone, said Kareem Babatunde, a crypto user in Nigeria. You lose assets and then the remaining assets you dont lose, lose their value.
The same characteristics that make crypto attractive for investors, make them glaring red on the heatmap of threat actors. its a lucrative pursuit for hackers and threat actors, said Eric Jardine, Cybercrimes Research Lead at Chainalysis, a company that provides data, intelligence, and forensics on cryptocurrency. The open-source software that many of the platforms run on makes it easy for hackers to find vulnerabilities they can later explore.
And of course, since the crypto wallets where stolen assets are sent are anonymous and the platform isnt regulated, it can be hard to track and retrieve funds, and much harder to tie incidents to an identity.
Chainanalysis has sometimes worked with law enforcement to track stolen funds by looking at how money moves from the accounts, which is of course recorded on a public ledger. The same public ledger that promises anonymity becomes a public record that tracks every transaction. Chainanalysis tracks every transaction until the stolen fund is sent to a wallet with an identity, often at the point when it needs to be converted into actual money.
But not everyone has access to this tool, and threat actors can find ways around this too.
The issue remains that the crypto ecosystem itself needs to prevent the breaches before they happen. The security issue isnt due to a particular problem or code. Its much more due to how the ecosystem is, especially at the moment, Jardine said.
The one-stop check for security might mean regulations that enforce Know Your Customer protocols, security troubleshooting, and enforcements that hold platforms to specific security standards. But the entire premise of crypto has been built almost entirely on things that do not align well with regulations.
But regulations or no regulations, the crypto ecosystem would be better off without so many security incidents. The ecosystems next challenge is to find a way to fix that without becoming regulated.
In response to the vulnerabilities in the crypto ecosystem, industry initiatives and best practices are emerging. The emphasis on education and user awareness is also growing, with organizations offering resources to help individuals navigate the crypto landscape much more safely. But these initiatives only respond to known vulnerabilities. For an industry so young, theres still a lot of vulnerabilities, continued Jardine. It would seem only time can fix these problems.
As cryptocurrencies continue to evolve, finding the delicate balance between privacy, security, and user empowerment remains crucial.
Olatunji Olaigbe is a freelance journalist and Columnist with Inkstick. Hes a winner of the 2021 IOM West and Central Africa Migration Journalism Awards.
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Beyond the Yuck Factor: Cities Turn to ‘Extreme’ Water Recycling – Yale Environment 360
In downtown San Francisco, in a cavernous garage that was once a Honda dealership, a gleaming white-and-blue appliance about the size of a commercial refrigerator is being prepared for transport to a hotel in Los Angeles.
There, this unit, called a OneWater System, will be installed in the basement, where its collection of pipes will take in much of the hotels graywater from sinks, showers, and laundry. The system will clean the water with membrane filtration, ultraviolet light, and chlorine, and then send it back upstairs to be used again for nonpotable uses.
And again. And again.
There is no reason to only use water once, said Peter Fiske, the executive director of the National Alliance for Water Innovation, a division of the Lawrence Berkeley National Laboratory, in Berkeley. Just as natural systems use and reuse water repeatedly in a cycle driven by the sun, he said, we now have technologies to enable us to process and reuse water over and over, at the scale of a city, a campus, and even an individual home.
While centralized water reuse for nonpotable purposes has been around for decades, a trend called the extreme decentralization of water and wastewater also known as distributed water systems, or on-site or premise recycling is now emerging as a leading strategy in the effort to make water use more sustainable.
The concept is to equip new commercial and residential buildings as well as districts, such as neighborhoods and universities, with on-site recycling plants that will make water for nonpotable use cheaper than buying potable water from a centralized source. By driving down demand for potable water, which is costly to filter, treat, and distribute, the units will help manage water more efficiently. It is, many experts believe, the future of water. Eventually its hoped that buildings will be completely self-sufficient, or water neutral, using the same water over and over, potable and nonpotable, in a closed loop.
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Its not just a pipe dream. Proof of concept is unfolding in San Francisco, which in 2015 required all new buildings of more than 100,000 square feet to have on-site recycling systems. So far, six blackwater and 25 graywater systems are using the technology, and many others are in the works. (Blackwater comes from toilets, dishwashers, and kitchen sinks; graywater comes from washing machines, showers, and bathtubs.) The headquarters of the San Francisco Public Utilities Commission has a blackwater system, called the Living Machine, that treats its wastewater in engineered wetlands built into the sidewalks around the building, then uses it to flush low-flow toilets and urinals. The process reduces the buildings imported potable supply by 40 percent.
Recycling graywater alone can save substantial amounts of water. Using it to flush toilets and wash clothes reduces demand for new water by about 40 percent. Using recycled water for showers would eliminate another 20 percent of water demand, though the safety of that practice is being researched and is not yet permitted in San Francisco.
Ryan Pulley of Epic Cleantec holds a beaker of graywater. Right: A beaker of potable treated graywater. Ted Wood
To demonstrate its technology, Epic Cleantec, a water recycling company, has even brewed a beer called Epic OneWater Brew with purified graywater from a 40-story San Francisco apartment building.
With the meagdrought and water crisis on the Colorado, the Rio Grande, and other Western rivers, extreme decentralization is making its way to other places in the American West, including Colorado, Texas, and Washington State. And decentralized projects are ongoing in Japan, India, and Australia. There are serious pressures on fresh water supplies around the world, with climate change exacerbating shortages. A recent study found that more than half the worlds lakes have lost significant amounts of water over the last 30 years. By 2050, the UN estimates that 5 billion people could be subjected to water shortages.
This is the future of water for everybody, Newsha Ajami, director of Urban Water Policy at Stanfords Water in the West program, said of decentralized water systems and recycling. Its a slow-moving process, but at the end of the day considering all the scarcity a lot of communities are going to pick this up as a way of having economic development while having water security.
San Franciscos recycling systems are not water neutral. The largest building with an on-site system is the Salesforce Tower, a 61-story office, hotel, and residential tower that opened in 2018 and is the tallest building in San Francisco. Built by the Australian company Aquacell, the system cleans 30,000 gallons of sewage, sink, shower, and other wastewater each day and uses it for irrigation and toilet flushing, saving an estimated 7.8 million gallons of water a year. Thats the equivalent of the annual use of 16,000 San Franciscans, the company says. Outside water is still needed for potable uses. (In New York, the Domino Sugar Refinery redevelopment project, currently under construction on the Brooklyn waterfront, will recycle 400,000 gallons of blackwater a day.)
The San Francisco Public Utilities Commission, the water provider, estimates that there are a total of 48 reuse systems in operation and 29 more projects being planned in the city. By 2040, the agency says, its Onsite Water Reuse program will save 1.3 million gallons of potable water each day.
The technology for these buildings to capture and treat all their water to potable standards already exists. But the safety of direct reuse of recycled wastewater is still being studied, and U.S. regulations so far do not allow that. A fully circular system, in which water is reused on-site for both potable and nonpotable uses, is at least five to 10 years away in this country, experts say.
Alternative water sources available in a typical urban building. Pacific Institute
Centralized recycled water systems, by contrast, have been used for decades, though they too have rapidly grown as a solution to water shortages. Orange County, California, for example, is home to the worlds largest water recycling facility. It cleans 130 million gallons of blackwater a day in a process called indirect potable reuse. Highly treated wastewater, which would normally have been discharged into the ocean, is put through an advanced three-step purification process that includes micro-filtration, reverse osmosis, and disinfection with ultraviolet light and hydrogen peroxide. The output is injected into nearby groundwater, to be pumped up and treated to drinking-water standards by local utilities.
In water-short Singapore, the massive Changi Water Reclamation Plant cleans and purifies 237 million gallons of wastewater a day to potable standards.
But the new reuse paradigm fundamentally rethinks water systems, localizing them in much the same way that households and districts with rooftop and community solar have transformed energy systems away from centralized power plants.
The vanishing Rio Grande: Warming takes a toll on a legendary river. Read more.
New buildings and neighborhoods, said Fiske, of the National Alliance for Water Innovation, may someday no longer need to hook up to sewer lines and water supplies. People will be able to build without regard to connections to water infrastructure, simply by using the same water again and again in a virtually closed loop. The water that falls on the roof in most places in the world will be enough to sustain a home, predicts Fiske, citing a recent study that found that this approach could save at least 75 percent of water demand.
Premise recycling not only saves water, it can also save the cost of pumping water over long distances and the costs associated with digging up streets for replacement and installation of pipelines. Water is heavy, said Fiske, And we live on a planet with gravity. So use water where you live over and over again.
While in some situations decentralized systems are expected to save money by reducing the energy needed to pump water, in others situations they could require more electricity to pump water through a building.
The increased prevalence of water recycling will allow water to be cleaned to varying standards or different flavors according to its intended use, a concept called fit for purpose. Water to flush toilets, for example, doesnt need to be cleaned as thoroughly as drinking water.
The recycling systems being built in San Francisco are widely considered a success, and representatives from water-stressed cities around the world have come here to study the approach.
Epic Cleantec has designed a system that will provide 30,000 gallons a day for the Park Habitat office building, under construction in San Jose. Its blackwater system will be used to irrigate a living green wall on the towers 20-story exterior. The system collects water from rain, cooling towers, showers, toilets, and sinks, then circulates it through a multistep treatment process in the basement. The solids are separated, sterilized, and turned into a soil amendment.
A rendering of the Park Habitat office building, now under construction in San Jose, which will use treated wastewater to irrigate a living green wall. Hayes Davidson / Westbank
San Francisco has written the playbook and de-risked the whole process by smoothing the regulations needed to build these systems, said Aaron Tartakovsky, who founded Epic Cleantec with his father, Igor, and is its CEO. The technology to do this has been around for a long time. What has prevented the adoption of the technology has been regulatory hurdles. Without any established framework there was no way to get this done. What cities and states are doing is coming up with a clear playbook for how these systems can be operated safely and efficiently.
Tartakovsky said the systems Epic Cleantec is building cost from a few hundred thousand to a few million dollars. The return on investment takes about seven years, he says. After that, there are considerable ongoing savings on water and sewer costs that vary from building to building.
Heather Cooley, director of research for the Pacific Institute in Oakland, an independent organization that studies water sustainability, and an author of a report on distributed systems and water resilience, believes premise systems are essential for Californias water future. These on-site and distributed systems are an exciting addition to the range of tools to meet weather challenges, she said. They will help build resilience. However, she added, theres no silver bullet. Theyre not going to be applied in every building everywhere.
It might seem counterintuitive that the San Francisco Public Utilities Commission requires new buildings to reduce their consumption of city water: After all, the commission is in charge of selling that resource. But San Francisco has a policy of densification in the urban core. As three- and four-story buildings are replaced with 10- and 12-story buildings, the cost of building new water infrastructure and finding new water sources is soaring.
Premise recycling is also taking place in what are known as districts. The University of California, Davis, has a blackwater system used for irrigation, and new neighborhoods are rising with their own closed-loop recycling systems. In San Diego, for example, developers are building a large district system to recycle blackwater at a shopping center thats being converted into an office campus.
Neighborhood scale is the right scale for sustainability for recycled water, said Claire Maxfield, director of the San Francisco office of Atelier Ten, a London-based architecture firm.
Orange County, California's wastewater recycling plant, the largest in the world, puts treated wastewater through a three-step purification process. Mario Tama / Getty Images
Maxfield led the sustainability team that helped design an 11-acre mixed-use district system for Mission Rock, a neighborhood now under construction next to the San Francisco Giants ballpark. It will collect blackwater from a main sewer, filter it, then send it to all 17 of the neighborhoods buildings to be used for irrigation and toilet flushing. It works really well, and it works really cost effectively at the neighborhood scale, said Maxfield. It shares the cost, its good for resilience and environmental justice. Its better than telling everybody to solve this on their own.
A recent study found this approach to water recycling adds about 6 percent to the cost of a single home and 12 percent to the cost of a multifamily dwelling. But as the number of people using these systems increases, economies of scale come into play, making recycled water far less expensive than city water.
The Hydraloop, created in Holland, is one home-based technology on the market, a kind of water washing machine. It recycles up to 95 percent of a households water, disinfecting shower and washing machine flows to irrigate lawns, flush toilets, and fill swimming pools. Overall water consumption declines by 25 to 45 percent. A company in Vancouver makes a product called RainStick, which recycles shower water over and over while you shower.
What are the barriers to even wider-scale residential changes? The yuck factor, experts say. When we talk about reuse theres a lot of fear among builders and architects, said Maxfield, though she believes they can be overcome.
A quiet revolution: Southwest cities learn to thrive amid drought. Read more.
Thats why, she said, decentralization of water and waste systems appears to be destined to play a major role in a water-stressed world. No one talked about carbon 20 years ago in the design of buildings, Maxfield said. And now everyone does. Water is going to have that moment.
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Beyond the Yuck Factor: Cities Turn to 'Extreme' Water Recycling - Yale Environment 360
iDenfy partners with P100 – The Paypers
Lithuania-based fraud management service provider iDenfy has partnered with Poland-based cryptocurrency and financial service platform P100.
In the company press release, iDenfy officials talked about the importance of seamless onboarding and straightforward ID verification processes for crypto users, particularly given the decentralised nature of digital assets. As cryptocurrencies were founded on the principles of decentralization and inclusivity, they aim to support financial freedom while giving users more control over their assets.
Offering the best of both worlds, iDenfys solution is able to provide a seamless customer journey while combatting fraud by leveraging a multi-level security system encompassing both Know Your Customer (KYC) and Anti-Money Laundering (AML) procedures.
P100s goals and ambitions are in line with a security-first approach, which is why the financial service provider decided to implement iDenfys full-stack ID verification and AML screening software. P100 hopes that the identity verification integration will boost user confidence in the company by demonstrating its commitment to safeguarding accounts.
P100s app now has a new account creation process, which leverages iDenfys solutions to verify the identities of aspiring users and conduct cross-checks against various databases, including global sanctions lists, watchlists, and politically-exposed person (PEP) lists.
If iDenfys system detects that a potential customer belongs to a high-risk category, such as being on a sanctions list or being identified as a known money launderer, it provides an instant notification to P100. P100 can then take proactive measures to prevent the user in question from registering on the platform. Compliance officers stand to benefit the most from this automated procedure, as they are already burdened with keeping up with evolving regulations and handling large data amounts.
Some of the key highlights of the P100 app include access to a personal IBAN, a debit card, and a currency exchange. These features were designed to allow users to manage their finances and cryptocurrencies on a single centralised platform. The companys own encryption technology works in tandem with iDenfys software to provide security and sustain user confidence that their cryptocurrencies are safe.
iDenfy has partnered with multiple companies in 2023 with the aim of improving their onboarding processes. One such a business is rental services company June, which adopted iDenfys solutions in May 2023.
As a growing prop-tech company, June receives thousands of applications from individuals interested in renting with them. Until the iDenfy partnership, the company's application review process was entirely manual. Following this collaboration, customers interested in renting apartments via June gained the option to take a picture of their ID document and benefit from instant onboarding onto the June platform without the need for internal team supervision.
For more information about iDenfy, please check out their detailed profile in our dedicated, industry-specific Company Database.
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Paediatric Clinical Trials Market is projected to grow at a CAGR of 6.3% by 2033: Visiongain – Yahoo Finance
Visiongain Reports Ltd
As per the report by Visiongain, the Paediatric Clinical Trials Market was valued at US$20,189.9 million in 2022 and is projected to grow at a CAGR of 6.3% during the forecast period 2023-2033.
Visiongain has published a new report entitledPaediatric Clinical Trials Market:- Forecasts by Indication (Infectious Disease, Oncology, Autoimmune/Inflammatory Diseases, Respiratory Disorders, Mental Health Disorders, Other Indications), by Phase (Phase 1, Phase 2, Phase 3, Phase 4), Market Segment by Study Design (Interventional Studies, Observational Studies) AND Regional and Leading National Market Analysis PLUS Analysis of Leading Companies AND COVID-19 Impact and Recovery Pattern Analysis
Lack of awareness and knowledge gap with respect to efficacy and safety of drugs in paediatrics have led to increased use of off-label medications for treatment. The treatment flow is majorly based on the patient journey of adults that risk the well-being and health of children. Furthermore, paediatric clinical trials are required across ages from new-borns to 18 years and focused in therapy areas specific for this age group. Also, challenges in these trials persist such as heterogeneity, the informed consent, and age-specific studies. Owing to these factors, there is need to enhance paediatric clinical research.
Download Exclusive Sample of Report
How has COVID-19 had a Significant Negative Impact on the Paediatric clinical trials Market?
COVID-19 presents an opportunity for the Paediatric Clinical Trials Market players to play an expanded role in care. Due to the pandemic, many clinical trials were halted that resulted in delaying the clinical trial study process and further added cost burden to the companies. However, the pandemic has opened further avenues for decentralized clinical trials and virtual trials. This presents an opportunity for wider pool of patients affected by the disease and more validation of clinical endpoints. Due to the pandemic, access to patients for recruitment and enrolment have been hampered hence identifying patients has been a major challenge. Furthermore, due to uncertainty over the effects of COVID-19 on children has limited the participation and interest of parents/guardians in enrolling children for trials.
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How will this Report Benefit you?
Visiongains 233-page report provides 118 tables, 165 charts, and graphs. Our new study is suitable for anyone requiring commercial, in-depth analyses for the paediatric clinical trials market, along with detailed segment analysis in the market. Our new study will help you evaluate the overall global and regional market for Paediatric clinical trials. Get financial analysis of the overall market and different segments including indication, phase, study design, and capture higher market share. We believe that there are strong opportunities in this fast-growing paediatric clinical trials market. See how to use the existing and upcoming opportunities in this market to gain revenue benefits in the near future. Moreover, the report will help you to improve your strategic decision-making, allowing you to frame growth strategies, reinforce the analysis of other market players, and maximise the productivity of the company.
What are the Current Market Drivers?
High Prevalence of Diseases Among Children
Most common preventable and treatable infectious diseases in children include malaria, pneumonia, diarrhoea, HIV and tuberculosis. High mortality and prevalence of such diseases is expected to drive market growth as there is increasing need for novel therapies. Pneumonia, diarrhoea and malaria accounted for 30% deaths among children below 5 years in 2019. Pneumonia is responsible for around 700,000 children annually across the globe. Diarrhoea accounted for 480,000 deaths among young children while malaria caused deaths of 274,000 children globally. Owing to such high prevalence, number of companies are focusing of developing new products and thus conducting clinical trial studies to enhance treatment options among children.
Usage of Decentralized Clinical Trials (DCTs)
Majority of paediatric clinical trials are adopting decentralization due to patient participation challenges. According to Clinical Trial Arena, 11.6% paediatric clinical studies have decentralization compared to 8% non-paediatric studies. Furthermore, based on therapy area, metabolic diseases have 14.4% decentralization vs 7.5% in non-paediatric studies in high income countries. Major reasons for high decentralization in metabolic diseases such as diabetes is that patients can self-monitor that requires less assistance. Such advantages can be further expanded to several therapy areas and help drive market growth.
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Where are the Market Opportunities?
Increase in investments for paediatric research showcases a significant opportunity for various national and international organizations. In 2020, global investments in Paediatric TB were US$ 91 million (10% of overall spending) which was 56% rise compared to 2019. However, the R&D expense on Paediatric research in TB is low which presents a broad opportunity for companies. Furthermore, according to an analysis, of the 20 pharmaceutical companies considered with total R&D projects of 1,073 only 69 or 6% were focused on children agedbelow 12 years. This showcases ample space for development and investments in paediatric clinical trials market.
With the advent of digitization, number of support services and technologies have been developed and introduced for paediatric clinical trials. Digital communication is widely been adopted in clinical trials for ease of asking questions by participants, discussions with the investigators, remote submission of informed consent, translation of supportive material in any language, and bond with communities through apps on personal devices. Furthermore, increasing use of cloud-based Software as a Service (SaaS) solution for activities such as capturing of patient reported outcomes data, remote monitoring, and telehealth services for supporting trial participants from the comfort of their homes. Such technologies will help to boost clinical trial process and also streamline complicated tasks.
Competitive Landscape
The major players operating in the paediatric clinical trials market are BMS, Charles River Laboratories, LabCorp Drug Development, GSK, ICON plc, IQVIA Inc., Novartis, Pfizer Inc., PPD Inc., Premier Research, QPS Holdings, Syneos Health, and The Emmes Company, LLC. These major players operating in this market have adopted various strategies comprising M&A, investment in R&D, collaborations, partnerships, regional business expansion, and new product launch.
Recent Developments
In May 2022, BMS received FDA approval for azacitidine (Vidaza) for paediatric patients with newly diagnosed juvenile myelomonocytic leukemia (JMML).
In March 2022, ViiV Healthcare received FDA approval for fixed dose combination of abacavir, dolutegravir and lamivudine for the treatment of paediatric patients weighing 10kgs to 25 kgs with HIV-1.
To access the data contained in this document please email oliver.davison@visiongain.com
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About Visiongain
Visiongain is one of the fastest-growing and most innovative independent market intelligence providers around, the company publishes hundreds ofmarket research reportswhich it adds to its extensive portfolio each year. These reports offer in-depth analysis across 18 industries worldwide. The reports, which cover 10-year forecasts, are hundreds of pages long, with in-depth market analysis and valuable competitive intelligence data. Visiongain works across a range of vertical markets with a lot of synergies. These markets include automotive, aviation, chemicals, cyber, defence, energy, food & drink, materials, packaging, pharmaceutical and utilities sectors. Our customised and syndicated market research reports offer a bespoke piece of market intelligence customised to your very own business needs.
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BEYOND LOCAL: Computer scientist explains why blockchain is a … – The Longmont Leader
The following article, written by Yu Chen, Binghamton University, State University of New York originally appeared on The Conversation and is published here with permission:
People hear a lot about blockchain technology in relation to cryptocurrencies like bitcoin, which rely on blockchain systems to keep records of financial transactions between people and businesses. But a crash in public trust in cryptocurrencies like TerraUSD and therefore a massive drop in their market value doesnt mean their underlying technology is also worthless.
In fact, there are plenty of other uses for this type of system, which does not rely on centralized storage and where many people can participate securely, even if they dont all know each other.
As a computer scientist exploring new technologies for future smart communication network technologies, I, along with many engineers and developers, have shown that blockchain technology is a promising solution to many challenging problems in trust and security of next-generation network-based applications. I see several ways blockchains are proving themselves useful that arent tied to cryptocurrency.
Modern global supply chains require a huge amount of information for the massive number of products being shipped around the world. They suffer from limits on data storage capacity, inefficient paper processes, disjointed data systems and incompatible data formats. These traditional centralized data storage methods cannot efficiently trace the origin of problems, like where a poor-quality product came from.
Storing information on a blockchain improves integrity, accountability and traceability. For example, IBMs Food Trust uses a blockchain system to track food items from the field to retailers. The participants in the food supply chain record transactions in the shared blockchain, which simplifies keeping track.
Data ownership and privacy are top concerns in the health care industry. Current centralized systems cannot meet all the diverse needs of patients, health service providers, insurance companies and governmental agencies. Blockchain technology enables a decentralized system for access control of medical records where all stakeholders interests are protected.
Blockchain systems not only allow health care service providers to securely share patients medical records but also enable patients to track who has accessed their records and determine who is authorized to do so.
Banking and finance benefit from integrating blockchain networks into their business operations. Instead of trying to develop cryptocurrencies with new or different capabilities, the financial sector has recognized that blockchain systems are a reliable way to store information about traditional currencies like the dollar, euro and yen, as well as financial products.
Blockchains provide consumers with the convenience of being able to monitor their transactions as they are processed, almost in real time from anywhere. Banks also benefit from blockchains, with the opportunity to conduct business between institutions more efficiently and securely.
Todays manual process of recording property rights is burdensome and inefficient. Traditional paper documentation is time-consuming, labor intensive, not transparent and vulnerable to loss. Blockchain technology eliminates inconvenience, inefficiency and errors, and reduces the cost by migrating the entire process into a digital form.
Blockchain systems allow owners to trust that their deed is accurate and permanently recorded. Remote access is particularly meaningful to people living in areas without sufficient governmental or financial infrastructure.
Validating votes and maintaining voter privacy seem like conflicting requirements. Blockchain systems hold promise as a means to facilitate a fair and transparent modern voting system. Because its almost impossible to tamper with a blockchain-enabled voting system, it can maintain a transparent electoral process.
In the November 2018 midterm elections in West Virginia, a blockchain-based voting system was used and found to be secure and reliable.
A smart city embeds information and communication technologies into its facilities, infrastructure and services to provide its residents a convenient, intelligent and comfortable living space. A smart city is essentially a network of many devices that can communicate with each other to share data. Connected devices can include peoples smartphones, vehicles, electrical meters, public safety monitoring systems and even homes.
These systems have performance, security and privacy requirements that centralized information systems cannot handle. Blockchain is a key networking technology for building smart cities because its able to optimize operations, enhance security guarantees and increase mutual trust among participants.
The future of information technology is all about decentralization. Todays centralized architecture fails to meet the increasingly diverse needs of people who want freedom to personalize their own services, control their digital assets and more easily participate in democratic processes. Blockchain is a key enabling technology for building any secure and durable decentralized information system.
Yu Chen, Professor of Electrical and Computer Engineering, Binghamton University, State University of New York. This article is republished from The Conversation under a Creative Commons license. Read the original article.
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BEYOND LOCAL: Computer scientist explains why blockchain is a ... - The Longmont Leader
Cardano vs Ethereum: Decentralization’s Wake-Up Call for the Crypto Industry and the Rise of Big Eyes Coin – Analytics Insight
The race for decentralization has become a pivotal point of discussion in the rapidly evolving world of cryptocurrency. One particular project making waves is Cardano, with its founder Charles Hoskinson recently stating that its decentralization efforts will serve as a wake-up call for other coins. In this article, we will delve into the similarities and differences between Cardano and other notable players in the industry, such as Ethereum, BIG, FLOKI, and ADA. We will also explore the innovative approach of Big Eyes Coin, a community token aiming to shift wealth into the DeFi ecosystem while supporting environmental causes.
Cardano, often referred to as the Ethereum killer, is a blockchain platform that stands out for its commitment to decentralization and rigorous scientific approach. Founded by Charles Hoskinson, one of the co-founders of Ethereum, Cardano utilizes a unique proof-of-stake consensus algorithm called Ouroboros. This approach ensures security, scalability, and sustainability while significantly reducing energy consumption compared to traditional proof-of-work systems.
Cardanos roadmap focuses on a phased approach to development, comprising multiple stages such as Byron, Shelley, and Goguen. Each stage introduces new features and functionalities, ultimately leading to full decentralization. By enabling stakeholders to participate in the decision-making process and actively run network nodes, Cardano strives to achieve true democratic governance within its ecosystem.
Ethereum, the second-largest cryptocurrency by market capitalization, is renowned for its pioneering role in smart contract technology. Unlike Cardano, Ethereum currently operates on a proof-of-work consensus mechanism. However, the Ethereum community has been actively working on transitioning to a proof-of-stake consensus model, known as Ethereum 2.0. This transition aims to address scalability concerns and reduce the networks environmental impact.
Smart contracts on Ethereum have unlocked immense possibilities, enabling the development of decentralized applications (DApps) and powering the growth of the decentralized finance (DeFi) ecosystem. Ethereums vibrant developer community and vast network effect have contributed to its prominence as a platform for innovation in the crypto space.
In the world of meme coins, Big Eyes Coin has emerged with a unique approach that combines cuteness, community engagement, and environmental impact. The tokens ecosystem revolves around Big Eyes, a cat with adorable, captivating eyes, who became an advocate for ocean conservation. By utilizing NFTs, Big Eyes Coin creates an inclusive blockchain ecosystem that offers exclusive content, events, and rewards to its active community.
Big Eyes Coins mission extends beyond meme coin hype, as it strives to generate wealth for its community while championing charitable causes. This alignment of financial growth and environmental stewardship sets Big Eyes Coin apart from traditional meme coins, injecting a sense of purpose and utility into its ecosystem. By supporting the DeFi space and emphasizing community engagement, Big Eyes Coin seeks to drive positive change while providing exciting opportunities for investors and meme coin enthusiasts.
In the quest for decentralization, both Cardano and Ethereum play pivotal roles, each with its unique approach and roadmap. Cardanos commitment to scientific rigor and its phased development strategy demonstrate its dedication to achieving true decentralization. Ethereums established presence and leadership in smart contract technology have propelled the growth of the DeFi ecosystem, albeit with the need for a transition to a more sustainable consensus mechanism.
As we explore the landscape of meme coins, Big Eyes Coin stands out by combining the charm of memes with a genuine commitment to environmental conservation. Its ecosystem offers a space for community engagement, financial growth, and support for charitable causes. Through its innovative use of NFTs, Big Eyes Coin aims to foster rapid growth, provide exclusive content, and reward its dedicated community.
The decentralization journey of Cardano, the groundbreaking innovations of Ethereum, and the unique vision of Big Eyes Coin highlight the dynamic nature of the crypto industry. As the sector continues to evolve, it is crucial for investors and meme coin enthusiasts to stay informed and engage with projects that align with their values. Visit https://bigeyes.space/ to learn more about the Big Eyes Coin project and join the community in shaping the future of crypto and environmental sustainability.
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Understanding Decentralization in Web3 Protocols | Latham … – JD Supra
Decentralization is the key innovation enabled by blockchain technology, and can have significant technological, economic, and legal implications for web3 companies and protocols. Decentralization remains hard to grasp and define despite its importance. In the web3 spirit of collaboration and open source, Latham has partnered with a16z Crypto to develop two matrices to help enumerate the components of decentralization.
The matrices articulate not only the various categories and factors of decentralization but also suggest indicators of various thresholds of decentralization with respect to each factor. Additionally, as decentralization must be assessed differently for different types of protocols and projects, we provide two different matrices for the following:
We hope this resource helps innovators, legal practitioners, investors, and policymakers to better understand and define decentralization. And we hope it can serve as a tool for builders to understand how to better pursue decentralization and self-assess their progress. This is intended to serve as a comprehensive starting point for defining decentralization, but we welcome feedback from all industry participants as both technology and standards evolve.
Learn more and access the Decentralization Matrix tools.
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Understanding Decentralization in Web3 Protocols | Latham ... - JD Supra
Dogetti: Embracing the Wake-Up Call of Cardano’s Decentralization – A Comparative Analysis with Cardano – Bitcoinist
Cardanos recent push towards decentralisation has captured the attention of both investors and industry enthusiasts. According to Charles Hoskinson, the founder of Cardano, this move is poised to serve as a wake-up call for other coins. In this article, we will delve into the similarities and differences between Cardano, Dogetti, and Solana, three notable players in the cryptocurrency industry.
By exploring their respective approaches to decentralisation and examining their unique features, we aim to provide valuable insights for readers seeking the next big crypto investment or meme coins with utility.
Cardano, often referred to as ADA, is a prominent blockchain platform that prioritises security, scalability, and sustainability. With a focus on peer-reviewed academic research and a rigorous development process, Cardano stands out as a promising investment option. One of its primary objectives is to facilitate the mass adoption of cryptocurrencies by addressing key challenges faced by the industry.
Decentralisation lies at the core of Cardanos philosophy. Unlike many other cryptocurrencies that rely on a single governing entity, Cardano aims to achieve full decentralisation through a multi-phase approach. The recent implementation of the Voltaire phase signifies a significant milestone, allowing ADA holders to actively participate in the networks governance and decision-making processes.
Drawing inspiration from popular meme coins like Dogecoin and Shiba Inu, Dogetti emerged as a community-oriented cryptocurrency. Dogettis unique selling proposition lies in the concept of building a united community, referred to as The Family, which fosters a sense of togetherness and exclusivity. By branding itself as a family rather than a mere community, Dogetti aims to create a distinct identity for its users and buyers.
The primary goal of the Dogetti project is to enhance the net worth of every member of The Family. Achieving this objective is made possible through a 2% reflection protocol that rewards holders on a regular basis. Moreover, Dogetti offers various forms of utility, establishing a solid foundation for long-term growth and sustainability. The projects strong emphasis on community engagement sets it apart from other meme coins and positions it as a potential contender in the crypto market.
Solana, a high-performance blockchain platform, has gained significant traction in the cryptocurrency ecosystem. Built to handle complex decentralised applications (dApps) and decentralised finance (DeFi) projects, Solana offers scalability and fast transaction speeds. This makes it an attractive option for developers and users seeking efficiency and seamless experiences.
While Solana shares the overarching goal of decentralisation with Cardano, its approach differs in terms of technological implementation. Solana leverages a unique consensus mechanism called Proof of History (PoH) alongside Proof of Stake (PoS) to achieve fast and secure transactions. Additionally, Solanas ecosystem supports an array of DeFi projects, providing users with opportunities for yield farming, lending, and more.
While Cardano and Solana have established themselves as industry leaders with their focus on decentralisation and technological advancements, Dogetti brings something unique to the table. By merging the excitement of meme coins with a dedicated community, lovingly called The Family, and a 2% reflection protocol that increases members net worth, Dogetti offers a distinct investment opportunity. Embrace Dogettis blend of fun, community, and tangible value, and discover a project that captures the best of both worlds in the crypto space.
Embark on an exciting journey into the memetic crypto world with Dogetti as your guide. Explore the potential applications, investment opportunities, and cultural significance of Dogetti. Join us as we navigate this thrilling landscape, providing insights and knowledge for readers seeking the next big memetic crypto sensation.
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Website: https://dogetti.io/
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Disclaimer:This is a paid release. The statements, views and opinions expressed in this column are solely those of the content provider and do not necessarily represent those of Bitcoinist. Bitcoinist does not guarantee the accuracy or timeliness of information available in such content. Do your research and invest at your own risk.
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