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Pistoia Alliance predicts a focus on the fight against antimicrobial resistance and a surge in quantum computing research for 2022 – Bio-IT World

Boston, US, 22 November 2021: The Pistoia Alliance, a global, not-for-profit alliance that advocates for greater collaboration in life sciences R&D, has today outlined predictions for the life sciences industry in 2022. The predictions come from three experts recently appointed by the Alliance to drive collaboration efforts across its three key themes. Their insights span the urgent fights against antimicrobial resistance, the potential of quantum computing and commercial space travel, and autonomous laboratories. Throughout 2021, digital transformation has continued to accelerate and the pharmaceutical industry has further embraced collaboration, both of which will underpin success in emerging areas in the next 12 months.

Linda Kasim, Empowering the Patient theme lead, Pistoia Alliance: In 2022, the renewed focus on the fight against super bugs and antimicrobial resistance (AMR) will be prioritized. This will be primarily driven by public-private partnerships, funding from philanthropic organizations, governments and international bodies to incentivize research. The public sector must quickly increase investment into AMR research, or the cost to national economies and public health could be devastating. mRNA technologies will represent a rapid and valuable platform to be further exploited for vaccines against AMR infections.

Digital health platforms will also be more integrated seeking efficiency through harmonized data generation. The use of Self-Sovereign Identities within healthcare solutions will expand. For these breakthroughs to happen, regulatory authorities must catch-up with the pace of research and innovation in health systems in 2022 by updating legal frameworks.

Imran Haq, Emerging Science and Technology theme lead, Pistoia Alliance: Driven by macro geopolitical trends and Big Tech, emerging technologies are being developed increasingly rapidly. Reflecting this, deal making in the quantum space will continue to grow a pace in 2022. As the buzz around the sector increases, will this be the year we finally start to see translation of this buzz into early versions of applications and use cases in the pharma industry? A likely quantum use case could be to improve supply chain efficiency. Big promises have been made during COP26, and large organizations, including pharma companies, must have net zero strategies. This is also an area we would like to explore with the Pistoia Alliances Quantum Computing Community of Interest.

Pharma is also going to play an increasingly critical role in space exploration. As plans to launch a commercial space stationfrom companies like Blue Origin accelerate, pharma should be engaged to ensure humans are healthy and can survive in the long term in extreme environments. 2022 is the time to think how we could be molding and driving forward health in space.

Anca Ciobanu, Improving the Efficiency and Effectiveness of R&D theme lead, Pistoia Alliance: Efficiency in R&D is on an exponential growth path as more pharma and biotech organizationspartner with AI and robotics companies, enabling a more automated drug discovery process. In 2022, the major tech players will increase their focus on the life sciences and will play an important role in developing new products and initiatives. The application of new technologies will not only empower scientists to conduct experiments more efficiently, but it will also help them make more breakthrough discoveries. As companies continue to invest resources in launching or improving their autonomous labs, researchers will need upskilling in data science, to be able to program and interact with themachines.

The Pistoia Alliance has more than 150 member companies including major life science companies, technology and service providers, academic groups, publishers, and patient research groups. Members collaborate as equals on projects that generate value for the worldwide life sciences and healthcare ecosystem. To find out more about the Alliance and its portfolio of projects, click here: https://www.pistoiaalliance.org/category/projects/.

--ENDS

About The Pistoia Alliance:

The Pistoia Alliance is a global, not-for-profit members organization made up of life science companies, technology and service providers, publishers, and academic groups working to lower barriers to innovation in life science and healthcare R&D. It was conceived in 2007 and incorporated in 2009 by representatives of AstraZeneca, GSK, Novartis and Pfizer who met at a conference in Pistoia, Italy. Its projects transform R&D through pre-competitive collaboration. It overcomes common R&D obstacles by identifying the root causes, developing standards and best practices, sharing pre-competitive data and knowledge, and implementing technology pilots. There are currently over 150 member companies; members collaborate on projects that generate significant value for the worldwide life sciences R&D community, using The Pistoia Alliances proven framework for open innovation.

Media Contacts:

Spark Communications

+44 207 436 0420

pistoiaalliance@sparkcomms.co.uk

Tanya Randall

The Pistoia Alliance

+44 7887 811332

tanya.randall@pistoiaalliance.org

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The Future of Quantum Computing – The Business Standard

Quantum computing could be the solution to the challenges that are faced by quantum physicists. It has the power to change our fundamental understanding of reality, and it could soon become a reality.

Quantum computing is an area of research in which engineers, scientists, and technologists are trying to build a computer where information is represented at the quantum level.

Quantum computers would be able to solve problems that are not possible with classical computers or solve them much more quickly. Today's silicon-based computer chips use binary digits (bits) with values of either 0 or 1 for storing information. These bits exist in two states at any given time and can't represent both 0 and 1 simultaneously like qubits which can represent all values at once thanks to the quantum mechanics principle called superpositioning.

Classical Computers VS Quantum ComputersTo understand how quantum computing works, it's important to know the difference between the old (classical) way of computing and the new (quantum) way.

On classical computers, information is encoded into binary digits called "bits." These bits can be in one of two states: 0 or 1. A qubit also has two possible states - 0, 1, or both at once (superposition). This means that it can encode much more information than a binary digit. The physical world behaves according to quantum mechanics. So theoretically, if we want to simulate physical phenomena on a computer, we should use quantum mechanical principles as well

Now that we have made the switching and memory units of computers, known as transistors, almost as small as an atom, we need to find an entirely new way of thinking about and building computers. Quantum computers are not intended to replace classical computers, they are expected to be a different tool we will use to solve complex problems that are beyond the capabilities of a classical computer. A problem that requires more power and time than today's computers can accommodate is called an intractable problem. These are the problems that quantum computers are predicted to solve.

When you enter the world of atomic and subatomic particles, things begin to behave in unexpected ways. It's this ability that quantum computers take advantage of. By entering into this quantum area of computing where the traditional laws of physics no longer apply, we will be able to create processors that are significantly faster than the ones we use today. Sounds fantastic, but the challenge is that quantum computing is also incredibly complex.

That's precisely why the computer industry is racing to make quantum computers work on a commercial scale.

Quantum computers are different from traditional computers because they use quantum bits (qubits) instead of binary bits. One qubit can be in two states at the same time, which solves many problems that current computers don't. Moreover, quantum computing can solve highly complex problems by using "parallelism" to process many calculations at the same time. The downside to this technology is that it needs an enormous amount of energy for operations to work properly. For instance, IBM has said that qubits need about 100 milliwatts of power per operation whereas regular processors need about 10 kilowatts

The Quantum Revolution

The practical uses of quantum computers are still being researched and tested. In the future, it is possible that quantum computers will be able to solve problems that have been impossible to solve before. For example, they have the potential to be used for modelling molecules or predicting how a molecule will behave under different conditions.

We should also remember that a quantum computer is not faster than a regular computer - it's just more powerful. That means that "running" a program on a quantum computer will take just as long as on a regular computer - but with much better results because of their increased power.Quantum computers will allow for the storage and processing of data in ways that we cannot even comprehend today. They also offer more complex calculations than traditional computers and therefore can easily solve problems that would take years to solve on a traditional computer.

Some experts believe that they could be used to calculate complex formulas with no time limit, which will make them an invaluable tool in medical science, AI technologies, aeronautical engineering and so on. So far, quantum computing has been used to solve optimization problems, which are too complex for traditional computer models. It's also been used to study protein folding and drug interactions within the body.

Quantum computers are powerful computers that work on the principles of quantum mechanics. They use qubits, not bits to represent data and they can access potentially more than two values at the same time. Quantum computers will be able to break all of the encoding and encryption we have today. Quantum computing is changing the world of cybersecurity. Quantum computers are capable of running sophisticated simulations in parallel, making them much faster than classical computers. The ability to run simulations in parallel means that quantum computers can quickly find solutions to difficult problems. Quantum computers will disrupt many industries like finance, healthcare, and education.

While it's still unclear how big of an impact quantum computing will have on marketing in the future, there are already some significant uses happening now. One example is in ad targeting where companies can analyze customer behaviour with astounding precision by processing large amounts.

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Einsteins notes on theory of relativity fetch record 11.6m at auction – The Guardian

Albert Einsteins handwritten notes on the theory of relativity fetched a record 11.6m (9.7m) at an auction in Paris on Tuesday.

The manuscript had been valued at about a quarter of the final sum, which is by far the highest ever paid for anything written by the genius scientist.

It contains preparatory work for the physicists signature achievement, the theory of general relativity, which he published in 1915.

Calling the notes without a doubt the most valuable Einstein manuscript ever to come to auction, Christies which handled the sale on behalf of the Aguttes auction house had estimated prior to the auction that it would fetch between 2m and 3m.

Previous records for Einsteins works were $2.8m for the so-called God letter in 2018, and $1.56m in 2017 for a letter about the secret to happiness.

The 54-page document was handwritten in 1913 and 1914 in Zurich, Switzerland, by Einstein and his colleague and confidant Michele Besso, a Swiss engineer.

Christies said it was thanks to Besso that the manuscript was preserved for posterity. This was almost like a miracle, it said, since Einstein would have been unlikely to hold on to what he considered to be a simple working document.

Today the paper offered a fascinating plunge into the mind of the 20th centurys greatest scientist, Christies said. It discusses his theory of general relativity, building on his theory of special relativity from 1905 that was encapsulated in the equation E=mc2.

Einstein died in 1955 aged 76, lauded as one of the greatest theoretical physicists of all time. His theories of relativity revolutionised his field by introducing new ways of looking at the movement of objects in space and time.

In 1913 Besso and Einstein attacked one of the problems that had been troubling the scientific community for decades: the anomaly of the planet Mercurys orbit, Christies said.

This initial manuscript contains a certain number of unnoticed errors, it added. Once Einstein spotted them, he let the paper drop, and it was taken away by Besso.

Scientific documents by Einstein in this period, and before 1919 generally, are extremely rare, Christies said. Being one of only two working manuscripts documenting the genesis of the theory of general relativity that we know about, it is an extraordinary witness to Einsteins work.

Einstein also made major contributions to quantum mechanics theory and won the Nobel physics prize in 1921. He became a pop culture icon thanks to his dry witticisms and trademark unruly hair, moustache and bushy eyebrows.

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The future is Bitcoin according to South Park creators – Cointelegraph

South Park, the animated TV series that often tackles topical issues with a comedic twist, showed Bitcoin being used as a mainstream means of payment in the not too distant future.

In the Post COVID episode of its 24th season which aired Thursday, South Park depicted one of the shows protagonists, Stan Marsh, paying for a stay in a cheap motel using Bitcoin (BTC) roughly 40 years from now, when the pandemic is jokingly about to end for good. The fictional Super 12 Motel Plus in a future where nearly all brand names have plus and maxx included only accepts Bitcoin and other cryptocurrency, with the show having Marsh pay using a plastic card with the BTC logo and a QR code.

Its the future weve all decided centralized banking is rigged so we trust more in fly-by-night Ponzi schemes, said the motel clerk.

Many in the crypto space know South Park for its criticism of the United States governments and banks response following the 2008 financial crisis, popularized by the meme aaaand... its gone referring to Marsh losing money immediately after depositing it in a bank. Among the other future predictions in the recent episode are autonomous vehicles, holographic digital assistants and stand-up comedy becoming a shadow of itself amid woke culture.

Though referencing cryptocurrency and blockchain in mainstream media is somewhat commonplace now, this wasnt always the case. The first TV series to feature BTC was The Good Wife in January 2012, but others have gone on to use the emerging technology and financial tool for both comedy and drama. This year, James Spaders character in The Blacklist claimed to know the true identity of Satoshi, and The Simpsons showed the BTC price moving to infinity on an animated stock ticker feed.

Related: Reality show is casting crypto users locked out of their wallets

Bitcoin's appearance on the popular animated series comes as the price of the crypto asset has stayed mostly under $60,000 for more than a week. According to data from Cointelegraph Markets Pro, the BTC price is $59,237 at the time of publication, having fallen more than 14% since reaching an all-time high of $69,000 on Nov. 10.

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Stripe says it’s open to accepting crypto for payments, three years after ending bitcoin support – CNBC

Stripe isn't ruling out accepting cryptocurrency as a method of payment in the future, according to co-founder John Collison.

The online payments company ended support for bitcoin payments in 2018, citing the digital coin's notoriety for volatile price swings and a lack of efficiency in making everyday transactions.

"Crypto obviously means a lot of different things to a lot of different people," Collison said at a CNBC-moderated panel at the Fintech Abu Dhabi festival on Tuesday.

Collison said there were some aspects to crypto such as its use as a speculative investment that are "not that relevant to what we do at Stripe."

But, he added: "There have been a lot of developments of late with an eye to making cryptocurrencies better and, in particular, scalable and acceptable cost as a payment method."

Asked whether Stripe would start accepting crypto as a method of payment again, Collison said: "We don't yet, but I think it's not implausible that we would."

The company recently formed a team dedicated to exploring crypto and "Web3," a buzzword in tech that refers to a new, decentralized version of the internet.

The effort is being led by Guillaume Poncin, Stripe's head of engineering. Earlier this month, the company appointed Matt Huang, co-founder of crypto-focused venture capital firm Paradigm, to its board of directors.

Collison said there are a number of innovations emerging in digital assets that have potential, including solana a competitor to ethereum, the world's second-biggest digital currency to "Layer 2" systems like bitcoin's Lightning Network, which aim to speed up transactions and process them at a lower cost.

Founded in 2009, Stripe has quickly become the largest privately-held fintech company in the U.S. The company was last valued at $95 billion and counts the likes of Baillie Gifford, Sequoia Capital and Andreessen Horowitz as investors.

The company, which processes payments for the likes of Google, Amazon and Uber, has expanded into a number of other areas in finance lately, including loans and tax management.

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Pokmon GO Creator’s AR Platform Is Now Being Used To Hunt Bitcoin, Not Pocket Monsters – Nintendo Life

Image: Fold

Niantic, the studio being the smartphone hit Pokmon GO, has lent its AR platform to payments company Fold to create a new kind of 'catch 'em all' adventure but this time, players are hunting for the cryptocurrency Bitcoin rather than monsters.

Payments company Fold has leveraged Niantic's AR platform to create an in-app experience where users can earn Bitcoin by exploring a virtual environment based on their immediate surroundings, described by the firm as a "real-world metaverse".

Users will be able to discover and collect Bitcoin and other prizes around them using the app. Every 10 minutes, a new block containing a fresh prize is dropped in the vicinity of a player. By claiming the block, the user earns 'Satoshis', the smallest unit of Bitcoin, alongside other rewards. However, if you collect a 's**tcoins' or 'Poison Pills', you could end up losing all of the Bitcoin you've collected.

Here's how Fold describes the experience on its blog it's even cheeky enough to use a gif of Mario collecting coins in Super Mario World:

The AR experience acts as a natural extension of the Fold App which already gives you the ability to earn bitcoin going about your daily life: buying coffee, going shopping, paying bills, and even paying your taxes. While the experience is open to anyone, Fold Cardholders can collect extra spins and rewards boosts to increase their rewards on the Fold Card.

The complete experience will drop next year and will enable individuals to find, trade, and hide bitcoin and other rewards throughout the world IRL, and will also give merchants the ability to engage the community with incentives and offers. It all started with someone saying lets make PokemonGo but for bitcoin and ended with lets build a new way to exchange and share bitcoin with others.

Fold CEO Will Reeves also had this to say:

This is the easiest, most fun way to get your first piece of Bitcoin. Anyone can use our [Fold] app to earn Bitcoin and other rewards by exploring the world around them. For us, it's always been important to make participating in the Bitcoin economy easy for anyone, regardless of education or technical expertise.

What do you make of this venture? Let us know with a comment.

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Bitcoin Thanksgiving Gift, Why BTC Heads For Fresh Rally – NewsBTC

Bitcoin has been trading on the green side this Thanksgiving morning with a 4.1% profit in the 24-hour chart. Approaching a critical resistance level, BTCs price stands at $59,042 and could see more appreciation in the short if it manages to flip $60,000 to support.

Bitcoin has been rangebound for the past week with low volatility for the most part as the price was rejected close to $60,000 on Monday. According to QCP Capital, an institutional investor is most likely responsible for the price action and suppression of any serious momentum on BTCs price rally attempts.

Related Reading |TA: Bitcoin Breaking This Confluence Resistance Could Spark Recovery

This institutional investor has been increasing selling pressure when Bitcoin attempts to reclaim previous highs, the firm noted. QCP Capital suspects this player or players could be pushing BTCs price down to place bearish put options on Bitcoin and Ethereum.

In that sense, the general sentiment in the market has taken a dive as NewsBTC reported. Most operators have gone into fear mode but could enter extreme fear if the selling pressure causes Bitcoin to break further down. QCP Capital added:

We are betting that the market will consolidate instead of breaking lower. So we are taking the opportunity to short vols in BTC and ETH as well as take profit on our downside risk reversal position and flip to a topside skew.

As of press time, Bitcoins current rally into $60,000 seems fairly strong with support in the $55,000 to $58,500 area. According to the In/Out of the Money Around Price metric, over 3 million addresses bought 2 million BTC on these levels.

Jarvis Labs analyst Ben Lilly recently tried to answer the question that seems to be in every trader and investors mouth: has the Bitcoin bull-run ended? As seen below, BTCs price bullish momentum is valid as long as it stays above $43,000.

In support of the bullish thesis, Jarvis Labs records heavy institutional demand for Bitcoin. Historically when BTC sees these levels of an accumulation from large investors, future price action experiences a strong push to the upside.

Conversely, when BTC sees low demand from whales, it suggests a cycle has been reached. Ben Lilly added on the whale accumulation pattern for the past week:

() whales are starting to step in. And this change will likely be reflected on the 30-day chart in a couple weeks.

However, Jarvis Labs has been warning about the behavior in the Bitcoin derivatives sector during November. Funding rates across this sector have stayed highly positive and although they have decreased with the recent trend to the downside, they still suggest the market is overheated.

Related Reading | TA: Bitcoin Continues To Struggle, Why BTC Could Dive Below $55K

Therefore, another retest of the lows and a full market reset seems to still be in the cards. This could be the final sacrifice for Bitcoin to reach a new all-time high in 2021.

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Buy the Dip: Bitcoin Whales Accumulated Over $2.36 Billion in $BTC After Price Drop – CryptoGlobe

Bitcoin whales, defined as addresses or clusters of addresses holding between 100 and 10,000 $BTC, have reportedly accumulated a whopping $2.36 billion worth of the flagship cryptocurrency after its price started dropping, data shows.

According to cryptocurrency analytics firm Santiment, bitcoin whales accumulated about 40,000 BTC when bitcoins price dropped to a $56,000 low last week. Considering bitcoin is now trading at around $59,000 per coin, whales have accumulated well over $2.3 billion of the cryptocurrency.

According to Santiment, whales took advantage of a price drip driven by bearish sentiment to keep on accumulating more BTC. As Daily Hodl reports, the cryptocurrency analytics firm has revealed in a recent report that BTCs supply keeps moving off of exchanges, which is seen as a positive sign for the market.

Investors moving their BTC off of trading platforms implies they are looking to custody their own funds and arent looking to sell in the short term. This reduces selling pressure on the market and lowers the risk of a continued sell-off.

Santiment has also added that social sentiment for the flagship cryptocurrency is at its most bearish level in seven weeks. The firms weighed social sentiment tracker analyzes commentary on specific cryptocurrencies to determine whether investors are bearish or bullish. Per the firm, prices tend to top when sentiment is too high, and bottom out when it gets too bearish. It wrote that the FUD [Fear, Uncertainty, and Doubt] is a good sign of capitulation.

Looking at funding rates on Binance, Santiment noted that when BTC was trading above $60,000 these were in positive territory, which is indicative of trader over-confidence. Often, it added, prices overcorrect when this happens. Now, the firm wrote, things look far more neutral.

As CryptoGlobe reported, bitcoins third-largest whale address has added a total of 6,665 BTC to its stash over the last 11 days when the price of the flagship cryptocurrency started dropping. Blockchaindatashows the whale currently has 113,863.56 BTC in its wallet.

DISCLAIMERThe views and opinions expressed by the author, or any people mentioned in this article, are for informational purposes only, and they do not constitute financial, investment, or other advice. Investing in or trading cryptoassets comes with a risk of financial loss.

IMAGE CREDITFeaturedImageviaPixabay

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JPMorgan Lists Ethereum As A Better Investment Than Bitcoin – NewsBTC

Ethereum has proved itself be to a force to be reckoned with and big bank JPMorgan agrees. When it comes to performance, Ethereum has outperformed rival Bitcoin, although the latter remains the most valuable cryptocurrency in the space. However, if history is any indication to go by, then Bitcoin may not be in the lead for much longer.

Analysts at JPMorgan recently released a report on cryptocurrencies and their potential. Although the note acknowledged the ability of Bitcoin, it also puts Ethereum ahead of the leading cryptocurrency in coming years. The report based its argument on the utility of both assets. While Bitcoin is good for its monetary policy, Ethereum has proven to be even better.

Related Reading |Why This Crypto Billionaire Abandoned Ethereum

The JPMorgan note outlined how Etheruem could prove to be the better bet compared to Bitcoin in the long wrong. Bitcoin may still be the most valuable cryptocurrency, but with climbing interest rates, Ethereum could end up faring better.

The rise in bond yields and the eventual normalization of monetary policy is putting downward pressure on bitcoin as a form of digital gold, the same way higher real yields have been putting downward pressure on traditional gold, said the analysts.

This is because as interest and inflation rates rise, more investors will flock towards decentralized finance (DeFi) protocols, which offer more attractive interest rates than traditional finance. Given that majority of these DeFi protocols are built on the Ethereum blockchain, it will only drive more adoption in the digital asset, providing it more room to grow than Bitcoin.

In the note, JPMorgan also points to the budding NFT, gaming, and stable coins portion of the market. This makes it a safer bet than Bitcoin when it comes to investing in cryptocurrencies, which are infamous for their volatility. As interest rates rise, its underlying utility should be able to help it maintain its value, the note reads.

With Ethereum deriving its value from its applications, ranging from DeFi to gaming to NFTs and stablecoins, it appears less susceptible than bitcoin to higher real yields.

Analysts at world-leading bank JPMorgan also put forward other reasons that Ethereum could end up being a better investment option than Bitcoin. One of these was the fact that the altcoin has consistently outperformed Bitcoin year-over-year. The numbers for 2021 alone show a wide margin when both digital assets are compared side by side in terms of performance.

Related Reading |Reddit User Calls Out KuCoin Over $50,000 Stuck On Exchange

Ethereum has grown more than 500% in the year compared to Bitcoins 96%. If the asset maintains this rate, then it could very well surpass the market cap of Bitcoin in the next five years while returning higher gains for its investors.

In five years, Ethereum has grown to about half the total market cap of Bitcoin. Sitting at over half a trillion dollars, the digital asset surpassed giants like Visa, MasterCard, and JPMorgan to claim the 15th spot as the most valuable asset in the world.

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Macro Guru Raoul Pal Says Millennials Migrating to Bitcoin From Gold and Traditional Finance Heres Why – The Daily Hodl

Macro guru Raoul Pal is saying that millennial investors are opting to invest in Bitcoin (BTC) instead of traditional assets like gold.

In a new interview with Parallax Digital CEO Robert Breedlove, Pal says that the traditional answer to currency debasement was gold, but that is no longer the case with a new generation of investors.

The traditional answer was gold. It hasnt done great. Its done okay. Its done its job, but the problem is, the millennials cant generate wealth if gold defends your wealth [theres] nothing to defend. So, it becomes incredibly difficult to generate wealth. Bitcoin comes along and changes the equation.

The Real Vision CEO says that investors will gradually see the value of crypto and migrate to this new asset class.

It takes a long time for people to see it. This adoption takes a while, but people realize here is a technological construct that has ubiquitous global scarcity and, therefore, if we all perceive it to have value, then it shall be so. So, the migration begins and I think of it as a migration to this parallel financial system thats being built in front of your eyes.

He adds that the same thing happens with decentralized finance (DeFi) many do not yet fully understand the concept, but the space is bound to grow.

The rise of DeFi was the other huge thing that happened. People havent got their heads around what this means yet, but it is gigantic because, basically, people dont trust financial intermediaries any longer.

Pal clarifies, though, that peoples mistrust of financial intermediaries is not these institutions fault.

They want to blame somebody, so [they] blame the banks. It wasnt the banks fault. They just did the rational thing.

The result of the CNBC Millionaire Survey released in June shows that nearly half of millennials with at least $1 million in investable assets allocate at least a quarter of their wealth in crypto. In contrast, only 10% of older millionaires have more than a tenth of their wealth in digital assets.

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