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Ahead of their time – The People’s Defender

Bill Lewis began teaching computer science at PHS in 1979. (Provided)

By Ashley McCarty

Peoples Defender

Before there was Google, Facebook, or YouTube, 25 years ago in 1996, Peebles High School became one of the very first schools in the area to have a website.

As we were building the new high school buildings, the school district sent several teachers out to workshops around the state. At one of these workshops, they taught us a little bit about how to create a website. I had been teaching computers at PHS for a number of years already, so this was kind of an amazing thing to me that these tools made this. It was really possible for students to do this. At that time, Microsoft was behind a project called Schools on the Web. You could create a website and then upload it to them, and thats actually how we got started, said former PHS Computer Science Teacher Bill Lewis.

The original group of 11 students credited for creating the website were Amy Farquer, Dale Fitzpatrick, Cori Hanna, Mandy Hedrick, Amanda Howard, Jason Howard, Beth Myers, Justin Myers, Jake Phipps, Regina Smalley and Robyn Workman. Since then, nearly 400 students at PHS have been directly involved in its design and development.

[Back then] we used Notepad [to create the website]. While [during my tenure] we did upgrade to Notepad++, we continued to write the code for the entire website in hand-coded HTML. We hand wrote it, we never used web tools. I always felt like, for the students, if they hand-coded it, it gave them a better understanding of what was happening. If you can hand-code it, you can adapt to using web tools very easily, because you can understand the concepts behind it. Since then, David Vogler has replaced me as the computer teacher, and they continue to start off doing hand-coding, said Lewis.

Over the years, not only have students been able to learn the intricacies of HTML through the website, but they have learned how to create graphic images, design, as well as the value of writing content.

They learned how to create graphic images, such as gifs, jpegs, creating icons or headers. We were extremely frugal. In 25 years, we spent less than $1,000 total. We bought a couple of digital cameras over the years. We used Paintshop Pro instead of Photoshop, and we used that to teach them how to do graphic editing. Beyond the mechanics of writing the HTML and the graphic editing, it was learning to design; using the right colors as well as background wallpapers. There was also writing content, and [all of the aspects that go with that to do it properly], said Lewis.

Alongside working on the school website, students were encouraged to create pages about themselves.

They would get so excited about that. It was something a lot of them took a lot of pride in, he said. He recalls many personalized and thoughtful pages created by his students reflecting their hobbies, interests and their passions. Even without internet, these pages could be created and opened in a web browser.

Once it got started, I became very passionate about it. I always started off the year telling the students that I took a lot of pride in the fact that this was a website made by them, by the students. I had my hand in it, but for the most part, everything was done by the students. I took and take so much pride in that, said Lewis. Still very impassioned, Lewis dedicates two or three days each year to guest-instruct the class.

[Over the years the website] has taken on many forms. In the beginning, the website was very basic, but it was something, and we were proud of it. As students became used to seeing websites, they would want to do different things. One year, I remember the background on the school homepage looked like it was inspired by the Grateful Dead, Lewis said, laughing, even though something may not have been to my taste, I supported the kids, because it was their website, he said. Though Lewis was always adamant to make sure everything was in good taste and properly legible.

Since its inception in 1996, the website has been visited by every state and every continent except for Antarctica.

Shortly before I retired [in 2014], it had been visited by somebody from every state aside from two. I vowed that if those two states still hadnt visited by the time I retired, I was going to go there and log into the website myself, he said, laughing, but, that happened before I retired.

Over the years, Lewis has had the opportunity to bond with some of those individuals in other states and countries and make a plethora of fond memories.

According to Lewis, sometime between 2010-2012, the district moved to using a single hub website for the different school attendance areas. Despite this change, the original PHS website continues to be updated.

Since I left, theyve added a Twitter feed and integrated the school calendar which has upcoming school events. It has the bell schedule, the teachers, course descriptions, news from various clubs, sports schedules, graduation information and much more. The website the students make is a lot more personal, said Lewis. Aside from that, there is history.

There is a page on there about the history of PHS. One of the last big projects we took on before I retired was digitizing all of the old senior composites. Theyre all on there. A lot of people in the community were excited about it. Theres some information on there about the history of the buildings, and even the teaching staff. Theres a lot of formal history aside from the [history students have created just by creating the pages], said Lewis.

For those wishing to experience the deeply nostalgic and enrapturing content the PHS website has to provide, visit https://www.peebles.scoca-k12.org/.

It was something that, in my last several years at Peebles, I took a lot of pride in. I think that we created a new tradition that still continues. I hope to see it continue for many more years. If people visit the site, I think they will find many interesting and wonderful things, said Lewis.

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Computer Conservation – Harvard School of Engineering and Applied Sciences

Lily Xu knew from a young age how much the environment and conservation mattered to her.

By 9 years old, shed already decided to eat vegetarian because, as she put it, I didnt want to hurt animals.

Xu grew up believing her passions would always be separate from her professional interest in computer science. Then she became a graduate student in Milind Tambes Teamcore Lab, and everything changed.

Xu is now doing award-winning research into using machine learning and artificial intelligence to help conservation and anti-poaching efforts around the world. Her recent paper, Learning, Optimization, and Planning Under Uncertainty for Wildlife Conservation, won the 2021 INFORMS Doing Good with Good OR Student Paper Competition.

From our earliest conversations, it was crystal clear that Lily was very passionate about sustainability, conservation, and the environment, said Tambe, the Gordon McKay Professor of Computer Science at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS). This was also the reason our wavelengths matched and I went out of my way to recruit her and ensure she joined my group.

In the Teamcore Lab, Xu helped develop Protection Assistant for Wildlife Security (PAWS), an artificial intelligence system that interfaces with a database used by park rangers to record observations of illegal poaching and predict which areas are likely to be poaching hotspots. The system makes it easier for rangers to choose the best locations to patrol.

In 2019, Xu and the Teamcore Lab partnered with the Srepok Wildlife Sanctuary in Cambodia to test the efficacy of PAWS. At the time, the sanctuary only had 72 rangers to patrol an area slightly larger than the state of Rhode Island.

Our work with Cambodia was the most intensive collaboration with a park that weve had, said Xu. We had several months of meetings, and our interactions with them and the feedback they were giving us about the process really shaped the design of our algorithms.

Xu played a lead role in implementing field tests of the PAWS program. Through Tambe, Xu and her lab mates, Srepoks rangers greatly increased the number of poachers snares they removed throughout the sanctuary.

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Singapore’s first free, teacher-less computer science programme to be launched by 2022 – The Straits Times

SINGAPORE - People can expect to sign up for Singapore's first free, teacher-less computer science programme by 2022.

Offered by French non-profit university Ecole 42 and the Singapore University of Technology and Design (SUTD), the course will be open to anyone aged 18 and above, regardless of their background in coding or mathematics.

Supported by SkillsFuture Singapore, the new programme - dubbed 42 Singapore - aims to develop a pipeline of tech talent for the digital economy.

Instead of classroom-based lessons delivered by lecturers and textbooks, students will learn tech skills in areas such as cyber security and network infrastructure at their own pace, advancing through project-based learning and gamification.

The first cohort of 150 students under the new programme in Singapore is expected to start by the end of 2022, with recruitment done through one or more admissions exercises a year, said SUTD in a statement on Tuesday (Nov 23).

Admissions at Ecole 42 schools are highly competitive, with applicants being selected after an intensive four-week bootcamp known as the "Piscine" or French for swimming pool.

The brainchild of French businessman and billionaire Xavier Niel first opened in Paris in 2013, and has since grown to a network of 36 campuses worldwide.

At the signing of an agreement between the two universities on Tuesday, Education Minister Chan Chun Sing said the programme's emphasis on aptitude and skill-based admission is in line with the spirit of new policies rolled out by the Ministry of Education.

He said: "Since last year, the autonomous universities (in Singapore) have expanded their practice of aptitude-based admissions.

"They are now relying less on academic grades, and more on other yardsticks of merit such as the interests and non-academic achievements of applicants, so that a more holistic range of aptitude and attributes can be considered."

The partnership with Ecole 42 has been in the making since November 2019, Mr Chan said.

Hailing the French universityas a trailblazer in innovation, he lauded the curriculum for bringing together students from different backgrounds and training them with in-demand skills and industry knowledge through real world projects.

Education Minister Chan Chun Sing (second from right) at the SUTD-Ecole 42 MOU signing ceremony on Nov 23, 2021.PHOTO: SUTD

He called for more of such innovative models of teaching being applied for training in other sectors beyond the information communications technology sector.

Highlighting that the Covid-19 pandemic has restricted cross-border exchanges, Mr Chan said he is looking forward to further discussions between France and Singapore on how to resume student exchanges and more avenues to preserve interactions between students and faculty.

Ambassador of France to Singapore Marc Abensour, who also witnessed Tuesday's event, said that Singapore had about 500 students studying in France before the pandemic.

Reaffirming the long-standing relationship between the two countries in higher education, Mr Abensour called for closer collaboration in upskilling and reskilling their workforces.

Students at 42 Singapore will have access to workshops, events and competitions organised by the SUTD community.

In its statement, SUTD said it is still seeking industrial partnerships to co-support the new 42 Singapore programme.

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Northern College hosts gaming tournament and hopes to attract future students with a new computer program – CTV News Northern Ontario

SUDBURY -

Northern College's Timmins Campus is doing something different to connect with the community--it's hosting a local gaming group called 'Gold Hearted Fighters' for a Super Smash Bros. tournament.

Its a whole kind of other world, things that we dont normally do but were looking to expand and reach out into the community more and be a part of the places that we are," said Amanda MacLeod, a coordinator of marketing, communications and external relations with Northern College.

MacLeod said these participants are people they want to inform about the College's new dual credential program in its computer science program.

One of the program's coordinators and professors said graduates will receive more than a diploma from Northern College and a degree from Algoma University.

Youre also getting a number of different micro credentials as well and so what micro credentials are, theyre basically digital badges so depending on the courses you complete here, you get a digital badge that you can display on social media or if youre going to a job interview you can share that with your employer to show heres the proof right," said Eric Lapajne.

A participant in the gaming tournament and a computer technician student at Northern College said there are bound to be others like him who want a quality education without having to uproot to get one.

Just looking at various schools, most of them werent as regarded or were equally as regarded as the program here and the drive here was forty minutes and the drive to other schools was several hours so it made a lot more sense for me to come here," said Dustin Brousseau.

Students interested can get the new computer engineering technician diploma and a bachelor of computer science degree in just three years of full-time study.

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A chance to focus on an academic passion at Oxford – Harvard Gazette

Hometown: Naperville, Ill.Concentration: Government, Technology Science Track

Trisha Prabhu is dedicated to making the internet a safer place. At Harvard, Prabhu is concentrating in government on the tech science track, which looks at the unexpected consequences of technology and aims to create new solutions to conflicts between technology and society.

My goal will be to continue the work that Ive had the chance to do here at Harvard, where I look at the unforeseen consequences of technology and the internet on our society, Prabhu said. I think about how we can solve the internets harms and try to create a digital world that is more kind, inclusive, and fair.

Prabhu is the founder and CEO of ReThink Inc., an app that detects offensive digital content and allows users the opportunity to reconsider posting it online.She also holds several patents and was recently a Civic Digital Fellow at the U.S. Department of Health and Human Services, where she helped lead the KidneyX Accelerator to incentivize businesses and innovators to work on kidney care technology solutions.

At Oxford, Prabhu hopes to study the social science of the internet and public policy.

Being named a Rhodes Scholar is such a surreal, yet very special experience. More than anything, I just feel such immense gratitude for the people that have gotten me here, members of the Harvard community like my professors, who encouraged me to go after an opportunity like this and equipped me with the skills and confidence, Prabhu said. She noted that shes excited to join the exceptional community at Oxford, with smart changemakers who care deeply about the problems that they want to try to affect change on.

Hometown: Brossard, Quebec, CanadaConcentration: Applied Mathematics and Economics, Secondary in Philosophy

An applied mathematics and economics concentrator, Ramiz Razzak studies monetary and fiscal tools that can be used to manage economic crises, which typically disproportionately affect the most vulnerable. As part of his senior thesis, Razzak is investigating whether central banks should use interest rate policy to counteract the buildup of financial imbalances. His research is also looking at whether North American monetary policy has historically been responsive to changes in sentiment in credit markets.

At Oxford, Razzak hopes to continue this work, with a particular focus on how current economic tools affect financial stability and inequality. He intends to study economic and social history.

I really am passionate about that research, because I feel that people who are most vulnerable during those types of events are the ones that get hit first, he said. If we can get even a little bit more clarity in terms of how to go about doing a better job using monetary and fiscal tools, I think that we can have a big impact.

While hes unsure where his studies will take him, Razzak is sure about one thing: He eventually wants to return home to Canada to serve his community.

I dont know what form itll take, Razzak said. If its through monetary policy at the Bank of Canada or fiscal policy with the Department of Finance Canada, or even involvement in Quebec, I just know thats something that I hold dearly. I want to give back to a community in a country that has given so much to me.

Stephanie Mitchell/Harvard Staff Photographer

Hometown: Spanishtown, JamaicaSchool: Harvard Graduate School of Education

Tonia N. Williams sees her next chapter at Oxford as a chance to continue to pursue her academic passion for education a journey she began at Harvard last year. Williams, who is a masters student at the Harvard Graduate School of Education, will seek a doctorate in experimental psychology with a focus on developmental psychology.

Williams entered Vassar College with a desire to learn more about the intersections of computer science and education, and focused on psychology. By the end of college, she had a strong foundation in neuroscience and other physiological elements of psychology but wanted to expand her understanding of early childhood development.

That led to her HGSE degree and a position as a research assistant in the Spelke Lab at the Harvard Laboratory for Developmental Studies. At Oxford, she wants to continue learning about psychological research in early childhood development that can be used to improve education.

This whole process taught me to trust my instincts, said Williams. I almost applied for the Rhodes last year and didnt because I thought my application could be stronger this year. I followed my interests from computer science and education to physiological psychology and back to human development. My interests have pulled me in different directions, Ive trusted the process, and its all worked out.

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New algorithm could save lives: Predicts COVID-related intensive care unit resource use University of Copenhagen – EurekAlert

The COVID-19 pandemic is onthe rise in many European countries,andhospitals world wide are under maximum pressure.

Now, an innovative algorithm will help alleviate pressure wheneverhospitals are confronted by new waves of COVID. Researchers from the University of Copenhagen, among others, have developed the algorithm, which can predict the course of COVID patients' illnesses in relation to how many of them will be highly likely or unlikely to require intensive care or ventilation.

This is important for the allocation of staff across the hospitals in for example Denmark, explains one of the study's authors.

"If we can see that well have capacity issues five days out because too many beds are taken at Rigshospitalet, for example, we can plan better and divert patients to hospitals with more space and staffing. As such, our algorithm has the potential save lives," explains Stephan Lorenzen, a postdoc at the University of Copenhagens Department of Computer Science.

The algorithm uses individual patient data from Sundhedsplatform (the National Health Platform) including information about a patients gender, age, medications, BMI, whether they smoke or not, blood pressure and more.

This allows the algorithm to predict how many patients, within a one-to-fifteen day time frame, will need intensive care in the form of, for example, ventilators and constant monitoring by nurses and doctors.

Along with colleagues at the University of Copenhagen, as well as researchers at Rigshospitalet and Bispebjerg Hospital, Lorenzen developed the new algorithm based on health data from 42,526 Danish patients who tested positive for the coronavirus between March 2020 and May 2021.

Traditionally, researchers have used regression models to predict Covid-related hospital admissions. However, these models havent taken individual disease histories, age, gender and other factors into account.

"Our algorithm is based on more detailed data than other models. This means that we can predict the number of patients who will be admitted to intensive care units or who need a ventilator within five days with over 90 percent accuracy," states Stephan Lorenzen.

In fact, the algorithm provides extremely accurate predictions for the likely number of intensive care patients for up to ten days.

"We make better predictions than comparable models because we are able to more accurately map the potential need for ventilators and 24-hour intensive care for up to ten days. Precision decreases slightly beyond that, similar to that of the existing algorithmic models used to predict the course of illness in Covid cases," he elaborates.

In principle, the algorithm is ready to be deployed in Danish hospitals. As such, the researchers are about to begin discussions with relevant health professionals.

"We have shown that data can be used for so incredibly much. And, that we in Denmark, are lucky to have so much health information to draw from. Hopefully, our new algorithm can help our hospitals avoid Covid overload when a new wave of the illness hits," concludes Stephan Lorenzen.

What distinguishes the new algorithm from others

Most existing algorithms in the field do not take the gender, age and medical history of individuals into account. They look at the number of hospitalized COVID patients in need of intensive care on any given day. Based on this, along with mortality and new infection data, existing models try to predict how many people will be hospitalized tomorrow.

"For example, typical models cannot distinguish between younger or older people. Whether there are five people who are 80-years-old or more hospitalized, or five 25-year-old patients, has a major impact on the prediction in relation to what the probability of hospitalization is. Our new algorithm accounts for this," says Stephan Lorenzen.

Ethical considerations

Scientific Reports

Using machine learning for predicting intensive care unit resource use during the COVID-19 pandemic in Denmark

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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Student cyber competition team is fifth of 120 competing in DOE contest – UAH News

The HuntsvilleTechSupport team is, from left, Nolan Rodgers, Will Green, Dayton Hasty, Sydney Winters and Ethan Reiland.

Courtesy UAH Cyber Club

A University of Alabama in Huntsville (UAH) student team has placed fifth out of 120 teams in nationwide virtual competition at the recent three-week-long U.S. Department of Energy CyberForce Competition.

The computer and cybersecurity students call their team HuntsvilleTechSupport. An element of the Cyber Club at UAH, a part of the University of Alabama System, HuntsvilleTechSupport has been competing in Jeopardy-style capture the flag (CTF) competitions for a little over a year.

Jeopardy-style CTFs present competitors with a set of questions that reveal clues that guide them in solving complex tasks in a specific order. By revealing clues, contestants learn the right direction regarding techniques and methodologies that are needed. CTF involves a number of true-to-life cyber challenges that each result in a text-based flag. These challenges are worth points, depending on difficulty, and they mirror the challenges professionals would face.

Advised by Dr. Tathagata Mukherjee, an assistant professor of computer science, HuntsvilleTechSupport placed in the top three in the university team category in competitions including the local National Cyber Summit Cyber Cup Challenge and BSides Huntsville.

We have been fortunate enough to have students who are self-motivated and who work and learn on their own time, Dr. Mukherjee says.

Though we as faculty have tried to provide support to them, there is only so much we can do given the time that is required to prepare for these types of national competitions, he says. As a result, I will put the credit for this success with the students and all the faculty members that have taught them over their years at UAH. Without that solid grounding and the hard work of the students, this would not have been possible."

Team members are Sydney Winters of Catlettsburg, Ky., a sophomore in computer engineering; Will Green of Huntsville, a sophomore in cybersecurity engineering; Dayton Hasty of Shelbyville, Tenn., a senior in computer science; Nolan Rodgers of Columbia, Tenn., a junior in cybersecurity engineering; and Ethan Reiland of Downington, Pa., a sophomore in computer science.

It feels pretty good placing so high after we have worked so hard on this competition for the past few weeks while balancing end of the year tests and projects, says Green, who was team captain for this event. We have had a lot of CTF practice over the past year, but defense competitions are relatively new to most of our team members.

Though competition began three weeks beforehand, Green says the official competition day was Nov. 13.

The competition itself was virtual this year, but our team met both virtually and in person to get the network set up and compete, he says. This is an annual competition, UAH competed in 2018 and 2019, but did not in 2020 because 2020s competition was individual, not team-based.

During the CyberForce competition, teams were given a virtual network filled with vulnerabilities and misconfigurations and had to fix and secure the entire network.

In this years scenario, we were acting as the blue team of a hydropower company, tasked with hardening and securing our systems against cyberattacks including the industrial control system controlling a dam facility all while maintaining our required services, Green says. In the week leading up to the competition, we had to create security documentation which included all of the changes that we made, a network diagram and the reasons for the new mitigations we put into place.

Teams also had to submit a video to a C-Suite Panel, presenting what would be done in a fictional merger scenario to secure the network from incoming machines and networks, says Hasty, who is the president of the UAH Cyber Club.

On competition day, we had to make sure our network was completely secure while a red team attacked and tried to exploit known or new vulnerabilities, Hasty says. If the red team found a vulnerability and was able to gain access to one of our machines, we had to then mitigate that vulnerability.

The competitions CTF element was composed of challenges released on competition day for teams to solve while they dealt with keeping their networks secure from the red team.

Points were awarded based on keeping up critical services, usability of those services, solving anomalies, mitigating the red team's exploited vulnerabilities, securing our network beforehand, our security documentation and our C-Suite Panel video, Hasty says.

The future for HuntsvilleTechSupport includes more competitions.

As far as defense-based competitions go, we plan on competing in the National Collegiate Cyber Defense Competition next year, Hasty says. There are fewer cyber defense competitions than there are normal Jeopardy-style CTF competitions. We normally compete in a CTF every weekend, which is a good way to practice while earning our team points on the global leaderboard.

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COVID-19: Vitamin D may be able to ‘switch off’ lung inflammation – Medical News Today

Scientists are sharing insight into how vitamin D could help in severe COVID-19 cases by revealing how the vitamin functions to reduce hyper-inflammation caused by immune cells.

A new joint study by Purdue University and the National Institutes of Health (NIH) demonstrates how an active metabolite of vitamin D not a form sold OTC is involved in switching off inflammation in the body during infections such as COVID-19.

Since inflammation in severe cases of COVID-19 is a key reason for morbidity and mortality, we decided to take a closer look at lung cells from COVID-19 patients, said lead authors Dr. Behdad (Ben) Afzali, chief of the Immunoregulation Section of the NIHs National Institute of Diabetes and Digestive and Kidney Diseases, and Dr. Majid Kazemian, assistant professor of biochemistry and computer science at Purdue University.

The study appears in the journal Nature Immunology.

As part of the study, researchers analyzed individual lung cells from eight people with COVID-19.

They found that in these cells, part of the immune response to SARS-CoV-2 the virus that causes COVID-19 was going into overdrive and exacerbating inflammation in the lungs.

After administering vitamin D in test-tube experiments, they observed reduced lung cell inflammation.

They then dove further into how the vitamin achieved this.

They did this by turning to T helper cells also known as CD4+ cells which are a type of immune cell that stimulate the killer T cells and other white blood cells to mount an immune response.

T cells are known to play a role in severe and dangerous cases of COVID-19 by going into overdrive and leading to an often fatal phenomenon known as a cytokine storm.

The scientists found that in normal infections, Th1 cells, which are a subset of helper T cells that fights microbes within the cell, go through a pro-inflammatory phase. During this phase, the body clears the infection.

Shortly after, the system shuts down to move onto the anti-inflammatory phase.

The scientists discovered that vitamin D is key in speeding up this transition.

We found that in healthy T cells, the activation of the inflammatory gene program coincided with the activation of a vitamin D system within these cells. We, therefore, investigated how this vitamin D system works and what it does for healthy T cells before we tried to relate it back to COVID-19, Dr. Afzali and Dr. Kazemian told Medical News Today.

Whereas in COVID-19 infections, the scientists saw that the pro-inflammatory phase of Th1 cells did not switch off. They attributed this to either a vitamin D deficiency or an abnormality in the cells response to vitamin D.

As expected, by studying which genes were switched on in the immune cells from the lungs of eight patients, we found that their cells were in an inflammatory state, said the co-authors.

Dr. Afzali and Dr. Kazemian said they were somewhat surprised to identify the intracellular vitamin D system.

[T]raditionally vitamin D has been thought of as depending on the kidneys to activate it before it becomes functional. We found that T cells had a self-contained system to both fully activate and respond to vitamin D, independently of the kidneys, they said.

The researchers hypothesized that adding a highly concentrated intravenous vitamin D metabolite to existing treatments could further help people recover from COVID-19. But they have not yet tested this theory in clinical trials.

Previous studies establish links between vitamin Ds ability to reduce the inflammation caused by T cells and the severity of COVID-19.

But the authors stress that people should not take these results as a treatment recommendation, and much more work is needed.

[I]ts crucially important to note that this study did not test vitamin D treatment in people but analyzed lung cells from eight people who had severe COVID-19, said Dr. Afzali and Dr. Kazemian.

The results, although interesting, should not be taken to indicate that vitamin D is beneficial for either the prevention or treatment of COVID-19 or that its a substitute for other preventive and effective means of COVID-19 prevention, including vaccines, masks, and social distancing.

Dr. Ben Afzali and Dr. Majid Kazemian

Dr. Donald J. Alcendor, associate professor of pathology, microbiology, and immunology at Vanderbilt University School of Medicine, said the study offered clues to a possible mechanism that will need validation on a larger scale.

There is widespread belief among the general public that taking megadoses of vitamin D can protect you prior to or following testing positive for COVID-19. The science supporting these claims is still evolving and will require a large-scale control clinical trial going forward. Even more, the mechanism for how vitamin D affects COVID-19 is still unknown, he said.

Dr. Alcendor said that even though vitamin D is known to have immune-modulatory functions, it does not justify its use as a protective measure against COVID-19 infection, especially if one ignores COVID-19 mitigation practices.

He warned that attempting to take higher doses of fat-soluble vitamins such as vitamin D could be problematic for some people.

A normal diet with a daily generic multivitamin will provide you with the necessary vitamin D needed, he said.

The study suggests that vitamin D could be a therapeutic option for COVID-19 thanks to its role in hyper-inflammation.

This study reveals a potentially unique role that vitamin D plays in the activation of T-cell functions that regulate inflammation in COVID-19, and understanding these regulatory pathways may provide information that will lead to the development of novel therapies for the treatment of acute COVID-19, said Dr. Alcendor.

This key finding could lead to the development of novel therapies for multiple respiratory viruses. The potential for this study could be groundbreaking.

Dr. Donald Alcendor

Dr. Kazemian and Dr. Afzali maintain that we will have to wait for clinical trials for results.

There are a number of clinical trials actively studying the potential of vitamin D as an adjunct therapy for the treatment of COVID-19. When these studies have reported in, we will have a much better idea of the therapeutic role that vitamin D could play in inflammation caused by COVID-19, they said.

However, Dr. Alcendor said future research would need to answer a slew of questions:

[I]s this mechanism specific to COVID-19, or is it true for other respiratory infections? If this study was performed with specimens from influenza patients, would you get a similar result? Could this key finding provide information that would lead to novel therapies for multiple respiratory viruses?

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In MIT visit, Dropbox CEO Drew Houston ’05 explores the accelerated shift to distributed work – MIT News

When the cloud storage firm Dropbox decided to shut down its offices with the outbreak of the Covid-19 pandemic, co-founder and CEO Drew Houston05 had to send the companys nearly 3,000 employees home and tell them they were not coming back to work anytime soon. It felt like I was announcing a snow day or something.

In the early days of the pandemic, Houston says that Dropbox reacted as many others did to ensure that employees were safe and customers were taken care of. Its surreal, theres no playbook for running a global company in a pandemic over Zoom. For a lot of it we were just taking it as we go.

Houston talked about his experience leading Dropbox through a public health crisis and how Covid-19 has accelerated a shift to distributed work in a fireside chat on Oct. 14 with Dan Huttenlocher, dean of the MIT Stephen A. Schwarzman College of Computing.

During the discussion, Houston also spoke about his $10 million gift to MIT, which will endow the first shared professorship between the MIT Schwarzman College of Computing and the MIT Sloan School of Management, as well as provide a catalyst startup fund for the college.

The goal is to find ways to unlock more of our brainpower through a multidisciplinary approach between computing and management, says Houston. "It's often at the intersection of these disciplines where you can bring people together from different perspectives, where you can have really big unlocks. I think academia has a huge role to play [here], and I think MIT is super well-positioned to lead. So, I want to do anything I can to help with that."

Virtual first

While the abrupt swing to remote work was unexpected, Houston says it was pretty clear that the entire way of working as we knew it was going to change indefinitely for knowledge workers. Theres a silver lining in every crisis, says Houston, noting that people have been using Dropbox for years to work more flexibly so it made sense for the company to lean in and become early adopters of a distributed work paradigm in which employees work in different physical locations.

Dropbox proceeded to redesign the work experience throughout the company, unveiling a virtual first working model in October 2020 in which remote work is the primary experience for all employees. Individual work spaces went by the wayside and offices located in areas with a high concentration of employees were converted into convening and collaborative spaces called Dropbox Studios for in-person work with teammates.

Theres a lot we could say about Covid, but for me, the most significant thing is that well look back at 2020 as the year we shifted permanently from working out of offices to primarily working out of screens. Its a transition thats been underway for a while, but Covid completely finished the swing, says Houston.

Envisioning the Future Workplace: A Fireside Chat with Drew Houston of Dropbox

Designing for the future workplace

Houston says the pandemic also prompted Dropbox to reevaluate its product line and begin thinking of ways to make improvements. Weve had this whole new way of working sort of forced on us. No one designed it; it just happened. Even tools like Zoom, Slack, and Dropbox were designed in and for the old world.

Undergoing that process helped Dropbox gain clarity on where they could add value and led to the realization that they needed to get back to their roots. In a lot of ways, what people need today in principle is the same thing they needed in the beginning one place for all their stuff, says Houston.

Dropbox reoriented its product roadmap to refocus efforts from syncing files to organizing cloud content. The company is focused on building toward this new direction with the release of new automation features that users can easily implement to better organize their uploaded content and find it quickly. Dropbox also recently announced the acquisitionof Command E, a universal search and productivity company, to help accelerate its efforts in this space.

Houston views Dropbox as still evolving and sees many opportunities ahead in this new era of distributed work. We need to design better tools and smarter systems. Its not just the individual parts, but how theyre woven together. Hes surprised by how little intelligence is actually integrated into current systems and believes that rapid advances in AI and machine learning will soon lead to a new generation of smart tools that will ultimately reshape the nature of work in the same way that we had a new generation of cloud tools revolutionize how we work and had all these advantages that we couldnt imagine not having now.

Founding roots

Houston famously turned his frustration with carrying USB drives and emailing files to himself into a demo for what became Dropbox.

After graduating from MIT in 2005 with a bachelors degree in electrical engineering and computer science, he teamed up with fellow classmate Arash Ferdowsi to found Dropbox in 2007 and led the companys growth from a simple idea to a service used by 700 million people around the world today.

Houston credits MIT for preparing him well for his entrepreneurial journey, recalling that what surprised him most about his student experience was how much he learned outside the classroom. At the event, he stressed the importance of developing both sides of the brain to a select group of computer science and management students who were in attendance, and a broader live stream audience. One thing you learn about starting a company is that the hardest problems are usually not technical problems; theyre people problems. He says that he didnt realize it at the time, but some of his first lessons in management were gained by taking on responsibilities in his fraternity and in various student organizations that evoked a sense of being on the hook.

As CEO, Houston has had a chance to look behind the curtain at how things happen and has come to appreciate that problems dont solve themselves. While individual people can make a huge difference, he explains that many of the challenges the world faces right now are inherently multidisciplinary ones, which sparked his interest in the MIT Schwarzman College of Computing.

He says that the mindset embodied by the college to connect computing with other disciplines resonated and inspired him to initiate his biggest philanthropic effort to date sooner rather than later because we dont have that much time to address these problems.

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Where are all the hacktivists? – BCS

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The social networking boom empowered everyone to have a voice via the internet and allowed activists to conduct globally organised smart mobs, petitions, blogs, emails, social media campaigns, virtual sit-ins and, of course, to share information anonymously to authorities, media and social justice groups like investigative journalists.

Some argue that although digital activism achieves awareness building and mobilisation of people, the overall goal may not be the case in many instances, which is perhaps the reason for hacktivism to surface from time to time.

COP26 is at the forefront of global concern. Intergovernmental Panel on Climate Change (IPCC) documents leaked to the BBC through Greenpeace UKs team of investigative journalists revealed some nations lobbying to change UN recommendations for action.

Open sources report that protests are expected to be heightened on 6 November, the Global Day for Climate Justice, as thousands of protestors are expected to arrive from across the world. Some predict that hacktivists could target government organisations, local businesses and rail networks during the conference.

Alex Dowall, Detective Superintendent for Cyber Investigations at Police Scotland, said: We know criminals will exploit any opportunity for their own gain and COP26 will be no different.

Ideological-based attacks have been too random to be able to predict with great certainty. Some of the worlds most resourced security programs with excellent risk profiles proved that security threats cannot be solved, prevented or removed through technological or engineering approaches. These are testing times for those in security professions.

By the time this insight is published, the world will know if the hacktivists made a comeback motivated by climate change. However, does the occasion always have to be as important? There are intense issues other than environmental ones

It is well known that suppression is counterproductive. This tightly interlinked world requires cooperation and a commitment to peaceful coexistence across species, cultures and generations. Governments and global communities should recast hacktivists as a geo-socially networked community of sensors, who can be creatively engaged with policy makers in solving emerging global threats.

Dr Deepthi Ratnayake FHEA CITP MBCS is an experienced lecturer with proven skills in cybersecurity research. LinkedIn: linkedin.com/in/deepthiratnayake

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Where are all the hacktivists? - BCS

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